Tetanus Toxoid Loaded Nanoparticles from Sulfobutylated Poly(Vinyl Alcohol)-Graft-Poly(Lactide-co-Glycolide): Evaluation of Antibody Response After Oral and Nasal Application in Mice
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Summary
Antigen loaded NP prepared from surface modified polyesters combined with CT show considerable potential as a vaccine delivery system for mucosal immunization.
- Type
- article
- Published
- 2001-03-01
- Cited by
- 172
- References
- 31
- OpenAlex
- https://openalex.org/W236932217
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21192926
Keywords
Toxoid, Nasal administration, Tetanus, Vinyl alcohol, Antibody
References
- The Oral Absorption of Micro- and Nanoparticulates: Neither Exceptional Nor Unusual
- Biodegradable microspheres: vaccine delivery system for oral immunization.
- Dependence on particle size in the phagocytosis of latex particles by rabbit alveolar macrophages cultured in vitro.
- Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen.
- Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches
- Adsorption of proteins from solution at the solid-liquid interface.
- Adsorption/desorption of human serum albumin at the surface of poly(lactic acid) nanoparticles prepared by a solvent evaporation process.
- Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres.
- Systemic and mucosal immune responses of mice to aluminium-adsorbed or aluminium-non-adsorbed tetanus toxoid administered intranasally with recombinant cholera toxin B subunit.
- Salivary, gut, vaginal and nasal antibody responses after oral immunization with biodegradable microparticles.
- Comparison of poly(DL-lactide-co-glycolide) and polystyrene microsphere targeting to intestinal M cells.
- Sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide)s facilitate the preparation of small negatively charged biodegradable nanospheres.
- Oral Vaccine Models: Multiple Delivery Systems Employing Tetanus Toxoid a
- Immune Response to Nasal Delivery of Antigenically Intact Tetanus Toxoid Associated with Poly(l‐lactic acid) Microspheres in Rats, Rabbits and Guinea‐pigs
- Large molecule and particulate uptake in the nasal cavity: the effect of size on nasal absorption.
- New strategies for using mucosal vaccination to achieve more effective immunization.
- The Uptake and Translocation of Latex Nanospheres and Microspheres after Oral Administration to Rats
- Nanoparticle Uptake by the Rat Gastrointestinal Mucosa: Quantitation and Particle Size Dependency
- Interaction of antigens and antibodies at mucosal surfaces.
- Mechanisms of macromolecule absorption by the lungs
Cited by
- Nanomedicines for overcoming biological barriers.
- PLA-PEG particles as nasal protein carriers: the influence of the particle size.
- Nasal vaccination with poly(β-amino ester)-poly(d,l-lactide-co-glycolide) hybrid nanoparticles.
- DESENVOLVIMENTO DE NANOPARTÍCULAS DE PLA E PLA-PEG PARA ADMINISTRAÇÃO INTRANASAL DE ZIDOVUDINA
- Influence of particle size, an elongated particle geometry, and adjuvants on dendritic cell activation.
- Tetanus toxoid-loaded layer-by-layer nanoassemblies for efficient systemic, mucosal, and cellular immunostimulatory response following oral administration
- Molecular design of nanoparticle-based delivery vehicles for pneumonic plague
- Applications of Nanotechnology in Vaccine Delivery
- Recent advances in microparticle and nanoparticle delivery vehicles for mucosal vaccination.
- Effect of Surface Chemistry on the Immune Responses and Cellular Interactions of Porous Silicon Nanoparticles
- Cationically-modified nanoparticles for the pulmonary delivery of the telomerase inhibitor 2';-O-Methyl RNA for the treatment of lung cancer
- La frontera entre la Biología molecular y la Nanotecnología: impacto en la Medicina
- Nasal and pulmonary vaccine delivery using particulate carriers
- Non-spherical micro- and nanoparticles
- Immunogenic Properties of a BCG Adjuvanted Chitosan Nanoparticle-Based Dengue Vaccine in Human Dendritic Cells
- The Molecular Influence of Graphene and Graphene Oxide on the Immune System Under In Vitro and In Vivo Conditions
- Shape and size-dependent immune response to antigen-carrying nanoparticles.
- Adjuvants in micro- to nanoscale: current state and future direction.
- The role of branched polyesters and their modifications in the development of modern drug delivery vehicles.
- Drug Delivery Using Nanocarriers: Indian Perspective
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