Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis.
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Summary
New insights into the mechanisms of angiogenesis and stroma formation are provided, insights which are potentially applicable to a wide variety of disease states and which may lead to identification of new targets for therapeutic intervention.
- Type
- review
- Published
- 1999-01-01
- Cited by
- 791
- References
- 166
- OpenAlex
- https://openalex.org/W189480869
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44983836
Keywords
Vascular permeability, Angiogenesis, Vascular endothelial growth factor, Vascular endothelial growth factor C, Vascular endothelial growth factor B
References
- Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis.
- Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia.
- A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF.
- Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.
- Vascular leakage through intraendothelial channels induced by cholera toxin in the skin of guinea pigs.
- Fibrinogen influx and accumulation of cross-linked fibrin in healing wounds and in tumor stroma.
- Expression of vascular permeability factor/vascular endothelial growth factor by human granulosa and theca lutein cells. Role in corpus luteum development.
- Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules.
- Tumor-secreted vascular permeability factor increases cytosolic Ca2+ and von Willebrand factor release in human endothelial cells.
- Endothelial Cell Biology in Health and Disease
- Tumor Blood Circulation: Angiogenesis, Vascular Morphology and Blood Flow of Experimental and Human Tumors
- Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas.
- The mechanism of vascular leakage induced by leukotriene E4. Endothelial contraction.
- Expression of endothelial cell-specific receptor tyrosine kinases and growth factors in human brain tumors.
- A novel vascular endothelial growth factor, VEGF‐C, is a ligand for the Flt4 (VEGFR‐3) and KDR (VEGFR‐2) receptor tyrosine kinases.
- Increased brain tumor microvessel permeability after intracarotid bradykinin infusion is mediated by nitric oxide.
- Vascular Endothelial Cell Growth Factor Promotes Tyrosine Phosphorylation of Mediators of Signal Transduction That Contain SH2 Domains
- Accessibility of circulating immunoglobulin G to the extravascular compartment of solid rat tumors.
- Pathogenesis of ascites tumor growth: vascular permeability factor, vascular hyperpermeability, and ascites fluid accumulation.
- Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.
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- Arteriogenesis - is this terminology necessary?
- Molecular Mechanism and Role of Endothelial Monocyte Chemoattractant Protein-1 Induction by Vascular Endothelial Growth Factor
- Neuropilin-1-mediated Vascular Permeability Factor/Vascular Endothelial Growth Factor-dependent Endothelial Cell Migration*
- The Way that PEGyl-DSPC Liposomal Doxorubicin Particles Penetrate into Solid Tumor Tissue
- Mending the broken heart: ischemic preconditioning-stimulated myocardial angiogenesis.
- New molecular mechanisms of the unexpectedly complex role of VEGF in ulcerative colitis.
- The Transcription Factor MEF2C Negatively Controls Angiogenic Sprouting of Endothelial Cells Depending on Oxygen
- Vasculogenesis and Angiogenesis as Mechanisms of Vascular Network Formation, Growth and Remodeling
- MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug TH-302 in Pancreatic Cancer Xenografts
- Assessing tumor angiogenesis in histological samples.
- Untersuchungen zur Regulation der Expression des Bartonella-Adhäsin A (BadA) Gens von Bartonella henselae
- Numerical simulation of blood flow through permeable vascular network embedded in tumour porous interstitium
- Thérapie génique de l'angiogenèse tumorale ciblée par des cellules endothéliales immatures
- Synthesis and biological evaluation of plasminogen activation inhibitors as antitumour/antimetastasis agents
- Evaluation de la spectroscopie du proton par RMN à 3 Tesla sans antenne endorectale chez les patients présentant un cancer de prostate localisé traité par radiothérapie exclusive
- The hypoxic tumour microenvironment and metastatic progression
- Zielgerichtete Antiangiogenese mit Bevacizumab und vaskuläre Ereignisse
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