Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor.

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Summary

The present studies performed to test the generality as well as the specificity of 3i domain-induced inhibition of receptor activity and suggest that peptides derived from a G protein-coupled receptor might serve as antagonists of receptor/G protein interactions.

Type
article
Published
1994-06-03
Cited by
91
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0
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Keywords

Cell biology, Receptor, 5-HT5A receptor, Cytoplasm, Signal transduction

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