Characterization of immature T cell subpopulations in neonatal blood.
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Summary
The presence of immature populations of T cells in normal human neonatal blood exhibiting phenotypes characteristic of normal developing thymocytes and a previously undescribed cell phenotype is revealed.
- Type
- article
- Published
- 1984-07-01
- Cited by
- 64
- References
- 28
- Access
- Open access
- OpenAlex
- https://openalex.org/W149625240
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10526898
Keywords
Cord blood, Monoclonal antibody, Antigen, Peripheral blood mononuclear cell, Thymocyte
References
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- Lymphocyte subpopulations in the blood of newborn infants.
- Distribution of t lymphocyte subsets in the human bone marrow and thymus: an analysis with monoclonal antibodies.
- Discrepancy in expression ability of Tac antigen and Ia determinants defined by monoclonal antibodies on activated or cultured cord blood T lymphocytes.
- Newborn T cell suppression: early appearance, maintenance in culture, and lack of growth factor suppression.
- Blast transformation of lymphocytes from newborn human infants.
- Age-associated changes in subpopulations of human lymphocytes.
- Studies of human lymphocytes in the newborn and the aged.
- Immunoelectron microscopic identification of Langerhans cells using a new antigenic marker.
- Reactivity of Langerhans cells with hybridoma antibody.
- Monoclonal antibodies OKT 11 and OKT 11A have pan‐T reactivity and block sheep erythrocyte “receptors”
- Intrathymic and Extrathymic T Cell Maturation
- Cutaneous T‐cell lymphoma
- Monoclonal antibodies defining distinctive human T cell surface antigens.
- Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage.
- Use of Ranks in One-Criterion Variance Analysis
- Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells
- Functional and Developmental Compartments of Human T Lymphocytes
- Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
- A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.
Cited by
- Altered T lymphocyte phenotype at birth in babies born to atopic parents
- Ontogeny of human natural and acquired immunity.
- Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation.
- Rat Peripheral CD4+CD8+ T Lymphocytes Are Partially Immunocompetent Thymus-Derived Cells That Undergo Post-Thymic Maturation to Become Functionally Mature CD4+ T Lymphocytes1
- Milestones in umbilical cord blood transplantation
- The use of monoclonal antibodies in the in situ identification of T‐cell subpopulations in cutaneous T‐cell lymphoma
- Natural Killer (NK) and T Cell-Associated Surface Marker Expression Following Allogeneic and Autologous Bone Marrow Transplantation (BMT)
- Immunological analysis of umbilical cord blood cells
- Phenotypic and functional analysis of human T lymphocytes in early second‐ and third‐trimester fetuses
- No in vitro evidence for a decreased alloreactivity toward noninherited maternal HLA antigens in healthy individuals.
- Flow cytometric analysis of lymphocyte subpopulations in infants with congenital heart disease
- In vitro cytokine production and phenotype expression by blood mononuclear cellsfrom umbilical cords, children and adults
- Circulating CD4+CD8+ T lymphocytes in patients with Kawasaki disease
- Mononuclear cells from peripheral blood of adult donors and from cord blood are equally protected by alpha- and beta-interferons against infection with HTLV-I.
- Phenotypic characterization of immature lymphoid cells in human umbilical cord blood
- Neonatal CD4+ CD45RA+ T cells: precursors of adult CD4+ CD45RA+ T cells?
- Cord Blood Natural Killer Cells Are Functionally and Phenotypically Immature but Readily Respond to Interleukin-2 and Interleukin-12
- Air Pollution and Distributions of Lymphocyte Immunophenotypes in Cord and Maternal Blood at Delivery
- Characterization of mononuclear cell subpopulations in normal fetal peripheral blood.
- Feasibility of human trials to assess developmental immunotoxicity, and some comparison with data on New World monkeys
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