Lead-protein interactions as a basis for lead toxicity.

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Summary

High-affinity metal-binding proteins have been shown to play a role in mediating Pb inhibition of the octameric Zn-containing enzyme, ALA dehydratase, which may represent a fundamental mechanism by which Pb exerts toxicity.

Type
article
Published
1993-01-01
Cited by
259
References
0

Keywords

Biochemistry, Chemistry, Enzyme, Binding site, Carbonic anhydrase

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