Induction of vascular permeability enhancement by human tryptase: dependence on activation of prekallikrein and direct release of bradykinin from kininogens.
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Summary
It is concluded that tryptase induces VPE by releasing BK, primarily through prekallikrein activation, but also through direct release from kininogens, which indicates that this mast cell-derived proteinase contributes to kinin production in allergic diseases.
- Type
- article
- Published
- 1996-05-01
- Cited by
- 103
- References
- 0
- OpenAlex
- https://openalex.org/W100325461
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7877983
Keywords
Tryptase, Prekallikrein, Kininogen, High-molecular-weight kininogen, Chemistry
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