Application of DNA Microarrays in Pharmacogenomics and Toxicogenomics
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Summary
The development of DNA microarray technology and its use in expression profiling of possible signal transduction events elicited by these compounds, and its potential future applications in drug discovery and development in the pharmaceutical industry are presented.
- Type
- review
- Published
- 2002-12-01
- Cited by
- 61
- References
- 31
- OpenAlex
- https://openalex.org/W74848271
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1198412
Keywords
Toxicogenomics, Pharmacogenomics, Xenobiotic, DNA microarray, Biology
References
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Cited by
- RNA and DNA microarrays.
- New Strategies in Drug Discovery
- Variability of DNA Microarray Gene Expression Profiles in Cultured Rat Primary Hepatocytes
- Designing Toxicogenomics Studies that use DNA Array Technology
- Expression genomics of cervical cancer: molecular classification and prediction of radiotherapy response by DNA microarray.
- Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers.
- Spectroscopic characterization of fluorescein- and tetramethylrhodamine-labeled oligonucleotides and their complexes with a DNA template.
- Novel multistranded, alternative, plasmid and helical transitional DNA and RNA microarrays: implications for therapeutics.
- Analysis of host response to bacterial infection using error model based gene expression microarray experiments
- Application of DNA Microarrays in Occupational Health Research
- Emerging technologies and challenges for better and safer drugs
- Application of toxicogenomic tools in the drug research and development process.
- DNA microarrays and pharmacogenomics.
- Molecular approaches to the identification of biomarkers of exposure and effect--report of an expert meeting organized by COST Action B15. November 28, 2003.
- cDNA Microarrays – Providing Insight into Organism/Chemotherapeutic Interactions
- Gene Expression Signature and the Prediction of Lymph Node Metastasis in Colorectal Cancer by DNA Microarray
- Advances in pharmacogenomic research and development
- The Use of Toxicogenomic Data in Risk Assessment: A Regulatory Perspective
- Microarray technology--an intellectual property retrospective.
- Assessing natural variations in gene expression in humans by comparing with monozygotic twins using microarrays.
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