Analysis of Reelin function in the molecular mechanisms underlying Alzheimer’s disease
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Summary
It is shown that overexpression of Reelin in J20 AD mice rescues the dendritic spine loss documented for this mouse strain with consequent rescue of the cognitive deficits associated to this AD model, such as non-spatial recognition tasks (assessed by Novel Object Recognition test).
- Type
- dissertation
- Published
- 2013-10-16
- Cited by
- 0
- References
- 347
- Access
- Open access
- OpenAlex
- https://openalex.org/W44261157
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:141291263
Keywords
Neuroscience, Reelin, Psychology, Neurodegeneration, Context (archaeology)
References
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- Normal and pathological Tau proteins as factors for microtubule assembly.
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- Neurodegeneration with Tau Accumulation in a Transgenic Mouse Expressing V337M Human Tau
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