NKG2D in innate and adaptive immunity.
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Summary
The expression of “NK receptors” on T cells implies a role in adaptive, as well as innate, immunity, and these receptors are present on effector or memory T cells.
- Type
- review
- Published
- 2005-01-01
- Cited by
- 40
- References
- 44
- OpenAlex
- https://openalex.org/W43150469
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27897569
Keywords
NKG2D, Receptor, Interleukin 21, Biology, Acquired immune system
References
- Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
- NKG2D ligands: unconventional MHC class I-like molecules exploited by viruses and cancer.
- NK1.1+ thymocytes. Adult murine CD4-, CD8- thymocytes contain an NK1.1+, CD3+, CD5hi, CD44hi, TCR-V beta 8+ subset.
- A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-gamma/delta+ T lymphocytes. I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody.
- Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes.
- In vivo immunogenetics: from MIC to RAET1 loci
- Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity.
- Expression of the UL16 glycoprotein of Human Cytomegalovirus protects the virus-infected cell from attack by natural killer cells
- Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
- Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages
- Effects of Human Cytomegalovirus Infection on Ligands for the Activating NKG2D Receptor of NK Cells: Up-Regulation of UL16-Binding Protein (ULBP)1 and ULBP2 Is Counteracted by the Viral UL16 Protein1
- Critical Role of MHC Class I-Related Chain A and B Expression on IFN-α-Stimulated Dendritic Cells in NK Cell Activation: Impairment in Chronic Hepatitis C Virus Infection 1
- A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins.
- Cutting Edge: Toll-Like Receptor Signaling in Macrophages Induces Ligands for the NKG2D Receptor 1
- Molecular cloning and characterization of a novel murine T cell surface antigen, YE1/48.
- Intracellular Retention of the MHC Class I-Related Chain B Ligand of NKG2D by the Human Cytomegalovirus UL16 Glycoprotein1
- Binding of Escherichia coli adhesin AfaE to CD55 triggers cell-surface expression of the MHC class I-related molecule MICA
- A second lineage of mammalian major histocompatibility complex class I genes.
- An activating immunoreceptor complex formed by NKG2D and DAP10.
- ULBP4 is a novel ligand for human NKG2D.
Cited by
- Immunological aspects of axon injury in multiple sclerosis.
- Natürliche Killerzellen in der Leukämie- und Tumortherapie
- Structural and functional characterization of the protein-protein interaction between the HCMV immunoevasin UL16 and the NKG2D ligand MICB
- Two Novel NKG2D Ligands of the Mouse H60 Family with Differential Expression Patterns and Binding Affinities to NKG2D1
- Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells
- NK Cells Rapidly Reject Allogeneic Bone Marrow in the Spleen Through a Perforin‐ and Ly49D‐Dependent, but NKG2D‐Independent Mechanism
- Tumor-derived soluble MICs impair CD3(+)CD56(+) NKT-like cell cytotoxicity in cancer patients.
- Low numbers and altered phenotype of invariant natural killer T cells in recurrent varicella zoster virus infection.
- Copy number variation in the mouse genome: implications for the mouse as a model organism for human disease
- Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties.
- Thy1+ Nk Cells from Vaccinia Virus-Primed Mice Confer Protection against Vaccinia Virus Challenge in the Absence of Adaptive Lymphocytes
- IFN‐γ production dominates the early human natural killer cell response to Coxsackievirus infection
- NKG2D-mediated activation of cytotoxic lymphocytes: unique signaling pathways and distinct functional outcomes.
- Innate-like behavior of human invariant natural killer T cells during herpes simplex virus infection.
- NKG2D splice variants: a reexamination of adaptor molecule associations
- MIC and other NKG2D ligands: from none to too many.
- Phenotype and function of natural killer cells in systemic lupus erythematosus: excess interferon-γ production in patients with active disease.
- Role of Natural‐Killer Group 2 Member D Ligands and Intercellular Adhesion Molecule 1 in Natural Killer Cell‐Mediated Lysis of Murine Embryonic Stem Cells and Embryonic Stem Cell‐Derived Cardiomyocytes
- Decidual NK cells regulate key developmental processes at the human fetal-maternal interface
- Differential expression of natural killer activating and inhibitory receptors in patients with newly diagnosed systemic lupus erythematosus
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