Therapeutic Albumin Binding to Remove Amyloid-β
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Summary
Grifols' therapeutic albumin has undetectable content of Aβ40 and Aβ42 and consistently binds peptides containing the primary sequence of human Aβ.
- Type
- article
- Published
- 2012-03-02
- Cited by
- 51
- References
- 45
- OpenAlex
- https://openalex.org/W43070737
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24598059
Keywords
Albumin, Amyloid (mycology), Chemistry, Medicine, Biochemistry
References
- [Plasmapheresis: its use in multiple sclerosis and other demyelinating processes of the central nervous system. An observation study].
- Plaque‐associated disruption of CSF and plasma amyloid‐β (Aβ) equilibrium in a mouse model of Alzheimer's disease
- Immunoassay based on surface plasmon oscillations.
- The binding constant for amyloid Abeta40 peptide interaction with human serum albumin.
- Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels.
- 18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease.
- Beta Amyloid in Alzheimer’s Disease: Increased Deposition in Brain Is Reflected in Reduced Concentration in Cerebrospinal Fluid
- Plasmapheresis with a substitution solution of human serum protein (5%) versus plasmapheresis with a substitution solution of human albumin (5%) in patients suffering from autoimmune diseases.
- Antibody‐based approaches in Alzheimer’s research: safety, pharmacokinetics, metabolism, and analytical tools
- Albumin. 2. Guidelines for clinical use.
- P3‐253: Acute administration of CHF5074, a novel gamma‐secretase modulator, improves contextual memory in a transgenic mouse model of Alzheimer's disease
- Amyloid-beta peptides interact with plasma proteins and erythrocytes: implications for their quantitation in plasma.
- THE IMMUNE GLOBULINS.
- Brain to Plasma Amyloid-β Efflux: a Measure of Brain Amyloid Burden in a Mouse Model of Alzheimer's Disease
- Analysis of Heterogeneous βA4 Peptides in Human Cerebrospinal Fluid and Blood by a Newly Developed Sensitive Western Blot Assay*
- Albumin-binding function is reduced in patients with decompensated cirrhosis and correlates inversely with severity of liver disease assessed by model for end-stage liver disease
- Amyloid-targeted therapeutics in Alzheimer's disease: use of human albumin in plasma exchange as a novel approach for Abeta mobilization.
- Human serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanism.
- Albumin binding capacity (ABiC) is reduced in commercially available human serum albumin preparations with stabilizers.
- Practical aspects of the ligand-binding and enzymatic properties of human serum albumin.
Cited by
- In Vitro Amyloid-β Binding and Inhibition of Amyloid-β Self-Association by Therapeutic Albumin
- Several Direct and Calculated Biomarkers from the Amyloid-β Pool in Blood are Associated with an Increased Likelihood of Suffering from Mild Cognitive Impairment
- Treatment of Alzheimer disease using combination therapy with plasma exchange and haemapheresis with albumin and intravenous immunoglobulin: Rationale and treatment approach of the AMBAR (Alzheimer Management By Albumin Replacement) study.
- Aβ association inhibition by transferrin.
- Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model
- Amyloid β-interacting partners in Alzheimer's disease: From accomplices to possible therapeutic targets.
- A multipronged, nutritional-based strategy for managing Alzheimer's disease.
- Magnesium Therapy Prevents Senescence with the Reversal of Diabetes and Alzheimer’s Disease
- Treatment of Alzheimer disease using combination therapy with plasma exchange and haemapheresis with albumin and intravenous immunoglobulin: Rationale and treatment approach of the AMBAR (Alzheimer Management By Albumin Replacement) study.
- HSA targets multiple Aβ42 species and inhibits the seeding-mediated aggregation and cytotoxicity of Aβ42 aggregates
- Validation of Immunoassay-Based Tools for the Comprehensive Quantification of Aβ40 and Aβ42 Peptides in Plasma
- Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer’s Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial
- The Effect of Vitamin D Supplementation on Plasma Aβ in an Older Population: A Randomized Control Trial
- Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid β (Aβ) peptides in the monomer and protofibril states
- Plasma amyloid β 42/40 ratios as biomarkers for amyloid β cerebral deposition in cognitively normal individuals
- Longitudinal Neuroimaging Analysis in Mild-Moderate Alzheimer’s Disease Patients Treated with Plasma Exchange with 5% Human Albumin
- Serum Albumin's Protective Inhibition of Amyloid-β Fiber Formation Is Suppressed by Cholesterol, Fatty Acids and Warfarin.
- Fatty Acids Compete with Aβ in Binding to Serum Albumin by Quenching Its Conformational Flexibility.
- The binding of monomeric amyloid β peptide to serum albumin is affected by major plasma unsaturated fatty acids.
- ‘Amytrapper’, a Novel Immobilized Sepharose API Matrix, Removes Amyloid-β from Circulation in vitro
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