Decreased expression of uroplakin Ia is associated with colorectal cancer progression and poor survival of patients.
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Summary
Low expression of UPKIa was a promising predictor for poor outcome of colorectal cancer patients and further studies on the potential use of UpKIa as a therapeutic targetis are still needed.
- Type
- article
- Published
- 2014-07-15
- Cited by
- 4
- References
- 20
- Access
- Open access
- OpenAlex
- https://openalex.org/W42970924
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20167439
Keywords
Colorectal cancer, Medicine, Oncology, Internal medicine, Cancer
References
- Mammalian uroplakins. A group of highly conserved urothelial differentiation-related membrane proteins.
- Loss expression of uroplakin III is associated with clinicopathologic features of aggressive bladder cancer.
- High Expression of Human Uroplakin Ia in Urinary Bladder Transitional Cell Carcinoma
- Uroplakins in Urothelial Biology, Function and Disease
- Persistent uroplakin expression in advanced urothelial carcinomas: implications in urothelial tumor progression and clinical outcome.
- Uroplakin II as a promising marker for molecular diagnosis of nodal metastases from bladder cancer: comparison with cytokeratin 20.
- Uroplakin Ib gene transcription in urothelial tumor cells is regulated by CpG methylation.
- Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors.
- Functional domains in tetraspanin proteins.
- Epidemiology of colorectal cancer in Asia
- Reduced Expression of Uroplakin 1A Is Associated with the Poor Prognosis of Gastric Adenocarcinoma Patients
- Cloning of the human uroplakin 1B cDNA and analysis of its expression in urothelial‐tumor cell lines and bladder‐carcinoma tissue
- Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma.
- Distinct Glycan Structures of Uroplakins Ia and Ib
- Assembly of urothelial plaques: tetraspanin function in membrane protein trafficking.
- Selective Interactions of UPIa and UPIb, Two Members of the Transmembrane 4 Superfamily, with Distinct Single Transmembrane-domained Proteins in Differentiated Urothelial Cells (*)
- Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.
- [Dietary fibers and colorectal cancer. Experimental studies, epidemiology, mechanisms].
- 892: Persistent Uroplakin Expression in Advanced Urothelial Carcinomas: Implications in Clinical Outcome
Cited by
- Uroplakin expression in the male reproductive tract of rat.
- circNFIC suppresses breast cancer progression by sponging miR-658
- Reciprocal regulation of HIF-1α and Uroplakin 1A promotes glycolysis and proliferation in Hepatocellular Carcinoma
- Large-scale human tissue analysis identifies Uroplakin 1a as a putative diagnostic marker for urothelial cancer.
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