Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantation.

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Summary

It is concluded that alloreactive donor lymphocytes are associated with lung injury in this allogeneic BMT model and their ability to respond to host antigens even when systemic tolerance has been established suggest that the lung may serve as a sanctuary site for these host reactive donor T cells.

Type
article
Published
1998-10-01
Cited by
144
References
60
Access
Open access

Keywords

Medicine, Immunology, Graft-versus-host disease, Bone marrow, Minor histocompatibility antigen

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