Major alteration of lung microbiome and the host responses in critically ill COVID-19 patients with high viral load
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Summary
A critical link between respiratory microbiome alterations and ventilator-associated pneumonia in COVID-19 patients with higher SARS-CoV-2 viral loads in respiratory samples, elevated neutralizing antibodies, and reduced inflammatory cytokines is revealed.
- Type
- article
- Published
- 2024-11-12
- Cited by
- 6
- References
- 52
- OpenAlex
- https://openalex.org/W39532981
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:274016950
Keywords
Column (typography), Trapping, Order (exchange), Computer science, Geography
References
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- Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities
- Development of a Dual-Index Sequencing Strategy and Curation Pipeline for Analyzing Amplicon Sequence Data on the MiSeq Illumina Sequencing Platform
- What distinguishes highly pathogenic staphylococci from medium- and non-pathogenic?
- The dynamics of the pulmonary microbiome during mechanical ventilation in the intensive care unit and the association with occurrence of pneumonia
- Lung inflammation and disease: A perspective on microbial homeostasis and metabolism.
- Innate Immune Cell Suppression and the Link With Secondary Lung Bacterial Pneumonia
- Bacterial and viral respiratory tract microbiota and host characteristics in children with lower respiratory tract infections: a matched case-control study
- Impact of Host DNA and Sequencing Depth on the Taxonomic Resolution of Whole Metagenome Sequencing for Microbiome Analysis
- Transcriptomics of type 2 diabetic and healthy human neutrophils
- Identification of Clostridioides difficile-Inhibiting Gut Commensals Using Culturomics, Phenotyping, and Combinatorial Community Assembly
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
- Genomic diversity of SARS-CoV-2 in Coronavirus Disease 2019 patients
- Staphylococci in the human microbiome: the role of host and interbacterial interactions.
- Alveolar lipids in pulmonary disease. A review
- Mitochondria and microbiota dysfunction in COVID-19 pathogenesis
Cited by
- Longitudinal analysis of lung microbiome, immune response, and metabolism in ventilator-associated pneumonia: a cohort study
- The Role of the Respiratory Microbiome in Pneumonia.
- Airway microbiome dysbiosis in severe pneumonia: metagenomic evidence of pathogen expansion and commensal depletion
- Ventilator-Associated Pneumonia: Bridging Global Disparities Through Standardized Definitions and Transparent Reporting.
- The Gut–Lung Microbiome Crosstalk and Pulmonary Disease
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