Acute exposure to polystyrene nanoparticles promotes liver injury by inducing mitochondrial ROS-dependent necroptosis and augmenting macrophage-hepatocyte crosstalk
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Summary
A profound toxicity of environmental PSNP exposure is suggested by triggering macrophage necroptosis, which in turn induces hepatotoxicity via intercellular crosstalk between macrophages and hepatocytes in the hepatic microenvironment.
- Type
- article
- Published
- 2024-04-12
- Cited by
- 61
- References
- 72
- Access
- Open access
- OpenAlex
- https://openalex.org/W38610056
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:269111974
Keywords
Drug trafficking, Political science, Sentence, Criminology, Law
References
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- Ascochlorin induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages.
Cited by
- Polystyrene nanoplastics exposure causes erectile dysfunction in rats.
- Photoaging of Polystyrene-based Microplastics Amplifies Inflammatory Response in Macrophages.
- Cell Death Mechanisms in Human Cancers: Molecular Pathways, Therapy Resistance and Therapeutic Perspective
- Exposure to perfluorodecanoic acid impairs follicular development via inducing granulosa cell necroptosis.
- Exposure to polystyrene nanoplastics promotes premature cellular senescence through mitochondrial ROS production and dysfunction in pre-differentiated skeletal myoblasts.
- Polystyrene nanoparticles induce DNA damage and apoptosis in HeLa cells
- Biological Effects of Micro-/Nano-Plastics in Macrophages
- Oral Exposure to Nylon-11 and Polystyrene Nanoplastics During Early-Life in Rats
- Integrated transcriptomic and proteomic profiling reveals the anti-inflammatory mechanism of dihydroartemisinin in the treatment of acute liver injury by targeting CYBA and CYBB.
- Ferroptosis as a key player in the pathogenesis and intervention therapy in liver injury: focusing on drug-induced hepatotoxicity
- Effects of micro- and nanoplastic exposure on macrophages: a review of molecular and cellular mechanisms
- Nanotechnology in Hematology: Enhancing Therapeutic Efficacy With Nanoparticles
- Mitigating microplastic-induced organ Damage: Mechanistic insights from the microplastic-macrophage axes
- Mitophagy: A double-edged sword in tumor cell death regulation and therapeutic response.
- Combined Effects of Nano-Polystyrene and Heavy Metal Mixture on the Bioaccumulation of Heavy Metals and Physiological Changes in Macrobrachium rosenbergii
- Toxicological Profiling of Polystyrene Microplastics in Raw 264.7 Macrophages: Linking Microplastic Exposure to Immune Cell Impairment.
- Large-sized polystyrene microplastics induce oxidative stress in AML12 cells
- Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies
- Internalized polystyrene nanoplastics trigger testicular damage and promote ferroptosis via CISD1 downregulation in mouse spermatocyte
- Mechanism of PISD/SPG7-mediated mPTP opening in necroptosis of inflammatory HaCaT cells induced by nano-zinc oxide.
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