Characterization of drosophila nemo kinase, a conserved modulator of Wnt and TGF? signal transduction

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Summary

The results indicate that Nemo acts as an intracellular feedback inhibitor of Wg during wing development and that it is a novel Wg target gene, and a novel crosstalk between Wg and Dpp signaling is unveiled, in which Wg-dependent gene expression is suppressed by ectopic DPP signaling.

Type
dissertation
Published
2005-01-01
Cited by
0
References
138
Access
Open access

Keywords

Wnt signaling pathway, Signal transduction, Cell biology, Phosphorylation, Biology

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