Genomic characterisation of pulmonary subsolid nodules: mutational landscape and radiological features
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Summary
It is found that higher ratios of solid components in SSNs were accompanied by significantly higher mutation frequencies in EGFR, TP53, RBM10 and ARID1B, suggesting that these genes play roles in the progression of LUADs.
- Type
- article
- Published
- 2019-11-07
- Cited by
- 76
- References
- 27
- Access
- Open access
- OpenAlex
- https://openalex.org/W31699841
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:207945771
Keywords
Philosophy
References
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Cited by
- Undetectable circulating tumor DNA levels correlate with low risk of recurrence/metastasis in postoperative pathologic stage I lung adenocarcinoma patients.
- Predicting Lung Cancer Risk of Incidental Solid and Subsolid Pulmonary Nodules in Different Sizes
- Application of large-scale targeted sequencing to distinguish multiple lung primary tumors from intrapulmonary metastases
- Imaging genomics for accurate diagnosis and treatment of tumors: A cutting edge overview.
- Decoding the multicellular ecosystem of lung adenocarcinoma manifested as pulmonary subsolid nodules by single-cell RNA sequencing
- Mutational Pattern in Multiple Pulmonary Nodules Are Associated With Early Stage Lung Adenocarcinoma
- Investigating the association between ground-glass nodules glucose metabolism and the invasive growth pattern of early lung adenocarcinoma.
- Molecular Identification and Genetic Characterization of Early-Stage Multiple Primary Lung Cancer by Large-Panel Next-Generation Sequencing Analysis
- RBM10 Deficiency Is Associated With Increased Immune Activity in Lung Adenocarcinoma
- Molecular Alterations in Lung Adenocarcinoma With Ground-Glass Nodules: A Systematic Review and Meta-Analysis
- Comparison of Clinical and Pathological Characteristics Between Extremely Multiple GGNs and Single GGNs
- The Impact of EGFR Tyrosine Kinase Inhibitor on the Natural Course of Concurrent Subsolid Nodules in Patients with Non–Small Cell Lung Cancer
- Up-regulated tumor intrinsic growth potential and decreased immune function orchestrate the evolution of lung adenocarcinoma
- Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis
- Three-Dimensional Convolutional Neural Network-Based Prediction of Epidermal Growth Factor Receptor Expression Status in Patients With Non-Small Cell Lung Cancer
- Single‐cell RNA sequencing reveals the multi‐cellular ecosystem in different radiological components of pulmonary part‐solid nodules
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- Radiomics/Radiogenomics in Lung Cancer: Basic Principles and Initial Clinical Results
- Lung adenocarcinoma manifesting as subsolid nodule potentially represents tumour in the equilibrium phase of immunoediting
- The evolution of T-cell receptor repertoire in different stages of non-small cell lung cancer
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