Selective modulation of the cannabinoid type 1 (CB1) receptor as an emerging platform for the treatment of neuropathic pain.
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Summary
An overview of the chemotypes currently under investigation for the development of novel neuropathic pain treatments targeting CB1 receptors is provided.
- Type
- article
- Published
- 2019-05-22
- Cited by
- 16
- References
- 153
- Access
- Open access
- OpenAlex
- https://openalex.org/W31191856
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:91719001
Keywords
Geology
References
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- β-Arrestins: Regulatory Role and Therapeutic Potential in Opioid and Cannabinoid Receptor-Mediated Analgesia
- A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects
- Novel Triazolopyrimidine‐Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases
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- Ultrapure ajulemic acid has improved CB2 selectivity with reduced CB1 activity.
- Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain.
- Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial.
Cited by
- Insights into biased signaling at cannabinoid receptors: synthetic cannabinoid receptor agonists.
- The role of the endogenous neurotransmitters associated with neuropathic pain and in the opioid crisis: the innate pain-relieving system.
- Targeting Peripherally Restricted Cannabinoid Receptor 1, Cannabinoid Receptor 2, and Endocannabinoid-Degrading Enzymes for the Treatment of Neuropathic Pain Including Neuropathic Orofacial Pain
- CORAL: QSAR models of CB1 cannabinoid receptor inhibitors based on local and global SMILES attributes with the index of ideality of correlation and the correlation contradiction index
- Disability-Specific Genes NR1, NMDA-2D and CB1 Show Injury-Dependent Protein Expression in the Lumbar Spinal Cord of CCI Rats.
- Structural and Functional Insights into Cannabinoid Receptors.
- Synthetic cannabinoid receptor agonists: analytical profiles and development of QMPSB, QMMSB, QMPCB, 2F-QMPSB, QMiPSB, and SGT-233.
- Antiallodynic effect of PhAR‐DBH‐Me involves cannabinoid and TRPV1 receptors
- Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor.
- Cannabinoid receptor agonists from Conus venoms alleviate pain-related behavior in rats.
- The why behind the high: determinants of neurocognition during acute cannabis exposure
- Understanding the Molecular Mechanisms Underlying the Analgesic Effect of Ginger
- Understanding the Dynamics of the Structural States of Cannabinoid Receptors and the Role of Different Modulators
- Spinal cannabinoid receptor 2 activation alleviates neuropathic pain by regulating microglia and suppressing P2X7 receptor
- Cannabinoids in Medicine: A Multifaceted Exploration of Types, Therapeutic Applications, and Emerging Opportunities in Neurodegenerative Diseases and Cancer Therapy
- Virtual library docking for cannabinoid-1 receptor agonists with reduced side effects
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