LINK-A lncRNA functions in the metastasis of osteosarcoma by upregulating HIF1α
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Summary
It was concluded that LINK-A lncRNA participated in the metastasis of osteosarcoma by upregulating HIF1α; upregulation of LINK- A lnc RNA may serve as a potential diagnostic biomarker for patients with MO but not in those with NMO.
- Type
- article
- Published
- 2019-03-21
- Cited by
- 25
- References
- 20
- OpenAlex
- https://openalex.org/W31186711
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:109152991
Keywords
Art
References
- Cancer treatment and survivorship statistics, 2016
- Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial–mesenchymal transition by regulating HIF-1α via miR-138
- Increased expression of lncRNA HULC indicates a poor prognosis and promotes cell metastasis in osteosarcoma.
- Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis
- Osteosarcoma treatment - where do we stand? A state of the art review.
- Long non-coding RNAs: a new frontier in the study of human diseases.
- Targeting HIF-1 for cancer therapy
- Tumor metastasis: mechanistic insights and clinical challenges
- Microarray expression profile of long noncoding RNAs in human osteosarcoma.
- Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
- Osteosarcoma: Current Treatment and a Collaborative Pathway to Success.
- Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis
- The emerging role of lncRNAs in cancer
- Unique features of long non-coding RNA biogenesis and function
- Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.
- The LINK-A lncRNA Activates Normoxic HIF1α Signaling in Triple-negative Breast Cancer
- Cancer treatment and survivorship statistics, 2014
- Overexpression of lncRNA UCA1 promotes osteosarcoma progression and correlates with poor prognosis
- Hypoxia Promotes Gastric Cancer Malignancy Partly through the HIF-1α Dependent Transcriptional Activation of the Long Non-coding RNA GAPLINC
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method
Cited by
- Long noncoding RNAs in osteosarcoma via various signaling pathways
- Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer
- The Biological Role of the Long Non-coding RNA LINK-A in Ovarian Carcinoma
- Circulating lncRNAs HIF1A-AS2 and LINLK-A: Role and Relation to Hypoxia-Inducible Factor-1α in Cerebral Stroke Patients
- Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury
- Circulating Long Non-Coding RNAs as Novel Potential Biomarkers for Osteogenic Sarcoma
- Inhibition of LINK-A lncRNA overcomes ibrutinib resistance in mantle cell lymphoma by regulating Akt/Bcl2 pathway
- Increased long noncoding RNA LINK-A contributes to rheumatoid synovial inflammation and aggression
- Comprehensive analysis of differentially expressed lncRNAs and associated ceRNA networks in Patau syndrome
- A diagnostic and prognostic value of blood-based circulating long non-coding RNAs in Thyroid, Pancreatic and Ovarian Cancer.
- The emerging role of lncRNAs in the regulation of osteosarcoma stem cells.
- The Roles of Noncoding RNAs in the Development of Osteosarcoma Stem Cells and Potential Therapeutic Targets
- Oncogenic Dysregulation of Circulating Noncoding RNAs: Novel Challenges and Opportunities in Sarcoma Diagnosis and Treatment
- m6A Demethylase FTO Stabilizes LINK-A to Exert Oncogenic Roles via MCM3-Mediated Cell Cycle Progression and HIF-1α Activation
- Non-coding RNAs in metabolic reprogramming of bone and soft tissue sarcoma: Fundamental mechanism and clinical implication.
- A concise review of the regulatory, diagnostic, and prognostic implications of HOXB-AS3 in tumors
- Hypoxia inducible factor-1ɑ as a potential therapeutic target for osteosarcoma metastasis
- Emerging roles of long non-coding RNAs in osteosarcoma
- LINK-A: unveiling its functional role and clinical significance in human tumors
- The role of long non‐coding RNAs in the development of diabetic kidney disease and the involved clinical application
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