Organocatalytic C(sp3)-H Functionalization of 5-Methyl-2,3-dihydrofuran Derivatives with Trifluoropyruvates via a Sequential exo-Tautomerization/Carbonyl-Ene Process.
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Summary
An organocatalytic C(sp3)-H functionalization of 5-methyl-2,3-dihydrofuran derivatives with trifluoropyruvates with good chemoselectivity and easy scalability was achieved via a sequential exo-tautomerization/carbonyl-ene process, providing the biologically important CF3-substituted 2, 3-dilutefurans in high yields.
- Type
- article
- Published
- 2019-01-24
- Cited by
- 7
- References
- 47
- OpenAlex
- https://openalex.org/W30676022
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:59225360
Keywords
Political science
References
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Cited by
- Recent trends in catalytic sp3 C-H functionalization of heterocycles.
- CuOTf/TfOH-mediated tandem reaction of conjugated ene-yne-ketones: Synthesis of novel spiro dihydrofurans
- Chemodivergent Photocatalytic Synthesis of Dihydrofurans and β,γ‐Unsaturated Ketones
- Highly Diastereoselective Synthesis of Multifunctionalized Dihydrofurans by a K3PO4‐Promoted Michael Addition‐Alkylation Reaction
- HFIP-promoted synthesis of imidazo [1,2-a]pyridines containing CF3-substituted tertiary alcohols at room temperature
- Domino dehydration/intermolecular (enantioselective) ketone-ene reactions catalysed by a simple solid in batch and in flow
- Synthesis of Oxazoles Containing CF3-Substituted Alcohol Unit via Tandem Cycloisomerization/Hydroxyalkylation from N-Propargylamides with Trifluoropyruvates
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