Identifying the Best Marker Combination in CEA, CA125, CY211, NSE, and SCC for Lung Cancer Screening by Combining ROC Curve and Logistic Regression Analyses: Is It Feasible?
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Summary
Combined ROC curve and logistic regression analyses are effective for identifying the best markers for lung cancer screening and showed that a two-marker combination is more suitable than a multimarker combination for the serological screening of tumors.
- Type
- article
- Published
- 2018-10-01
- Cited by
- 98
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W30364165
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:53027142
Keywords
Breeder (animal), Breeder reactor, Nuclear engineering, Engineering, Political science
References
- Use of Biomarkers in Screening for Cancer.
- Diagnostic Value of Serum miR-182, miR-183, miR-210, and miR-126 Levels in Patients with Early-Stage Non-Small Cell Lung Cancer
- Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
- Preoperative serum CA125 is an independent predictor for prognosis in operable patients with non-small cell lung cancer.
- Serum biomarkers for assessing histology and outcomes in patients with metastatic lung cancer
- The assessment of the prognostic value of tumor markers and cytokines as SCCAg, CYFRA 21.1, IL-6, VEGF and sTNF receptors in patients with squamous cell cervical cancer, particularly with early stage of the disease
- Difference in mesothelin‐binding ability of serum CA125 between patients with endometriosis and epithelial ovarian cancer
- Prognostic value of serum CYFRA21-1 and CEA for non-small-cell lung cancer
- HE4 combined with CA125: favorable screening tool for ovarian cancer
- The Prognostic Significance of Pretreatment Serum CEA Levels in Gastric Cancer: A Meta-Analysis Including 14651 Patients
- Lung Cancer Screening Beyond Low-Dose Computed Tomography: The Role of Novel Biomarkers
- Carcinoembryonic antigen (CEA) as tumor marker in lung cancer.
- Tumor Markers (CEA, CA 125, CYFRA 21-1, SCC and NSE) in Patients with Non-Small Cell Lung Cancer as an Aid in Histological Diagnosis and Prognosis
- Utility of postoperative CEA for surveillance of recurrence after resection of primary colorectal cancer.
- Cancer screening in the United States, 2013
- Lung cancer screening.
- Serum CYFRA21-1 as an effective tumor biomarker for patients with nasopharyngeal carcinoma.
- Practice guidelines for tumor marker use in the clinic.
- Clinical observations on the association between diagnosis of lung cancer and serum tumor markers in combination.
- Combining multiple serum biomarkers in tumor diagnosis: A clinical assessment.
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- P-STAT3 and IL-17 in tumor tissues enhances the prognostic value of CEA and CA125 in patients with lung adenocarcinoma.
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- Lack of Efficacy of Combined Carbohydrate Antigen Markers for Lung Cancer Diagnosis
- Combined assay of Circulating Tumor DNA and Protein Biomarkers for early noninvasive detection and prognosis of Non-Small Cell Lung Cancer
- Application of Circulating Genetically Abnormal Cells in the Early-stage Diagnosis of Lung Cancer