Indoxyl sulfate (IS)-mediated immune dysfunction provokes endothelial damage in patients with end-stage renal disease (ESRD)
Explore this paper's citation graph
Summary
It is suggested that in ESRD, IS-mediated immune dysfunction may cause vascular endothelial cell damage and thus, this toxin plays a pivotal role in the pathogenesis of CVD.
- Type
- article
- Published
- 2017-06-08
- Cited by
- 114
- References
- 73
- Access
- Open access
- OpenAlex
- https://openalex.org/W28596556
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25272970
Keywords
Geography
References
- The physiological role of cytotoxic CD4+ T‐cells: the holy grail?
- Investigating the role of proinflammatory CD16+ monocytes in the pathogenesis of inflammatory bowel disease
- Uremic Toxicity: Present State of the Art
- Role of Indoxyl Sulfate in the Progression of Chronic Kidney Disease and Cardiovascular Disease: Experimental and Clinical Effects of Oral Sorbent AST‐120
- Down-regulation of CD28 expression by TNF-alpha.
- The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia.
- Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation
- Indoxyl sulfate induces skeletal resistance to parathyroid hormone in cultured osteoblastic cells.
- Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors
- Elevated pro-inflammatory CD4+CD28− lymphocytes and stroke recurrence and death
- Immune cell dysfunction and inflammation in end-stage renal disease
- IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly.
- Expansion of cytolytic CD4+CD28- T cells in end-stage renal disease.
- AH RECEPTOR LIGANDS IN CANCER: FRIEND AND FOE
- The pattern of excess cancer in dialysis and transplantation.
- Association of Graves’ Disease and Prevalence of Circulating IFN-γ-producing CD28− T Cells
- Mortality caused by sepsis in patients with end-stage renal disease compared with the general population.
- Production of interleukin-6, tumor necrosis factor alpha and interleukin-10 in vitro correlates with the clinical immune defect in chronic hemodialysis patients.
- Oxidative stress in uremia: nature, mechanisms, and potential consequences.
- Clinical epidemiology of cardiovascular disease in chronic renal disease.
Cited by
- The double‐edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation
- End‐stage renal disease, dialysis, kidney transplantation and their impact on CD4+ T‐cell differentiation
- Indoxyl Sulfate Generates Free Radicals, Decreases Antioxidant Defense, and Leads to Damage to Mononuclear Blood Cells.
- Microbial tryptophan catabolites in health and disease
- Clinical epidemiology of infectious disease among patients with chronic kidney disease
- The Impact of Uremic Toxicity Induced Inflammatory Response on the Cardiovascular Burden in Chronic Kidney Disease
- Induced pluripotent stem cell-derived endothelial progenitor cells attenuate ischemic acute kidney injury and cardiac dysfunction
- Higher risk of malignant neoplasms in young adults with end‐stage renal disease receiving haemodialysis: A nationwide population‐based study
- The impact of antihypertensive pharmacotherapy on interplay between protein-bound uremic toxin (indoxyl sulfate) and markers of inflammation in patients with chronic kidney disease
- Cranberries - potential benefits in patients with chronic kidney disease.
- Klotho restrain RIG-1/NF-κB signaling activation and monocyte inflammatory factor release under uremic condition.
- Indoxyl sulfate–induced TNF‐α is regulated by crosstalk between the aryl hydrocarbon receptor, NF‐κB, and SOCS2 in human macrophages
- Cohort Profile: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort in Korea
- Indoxyl Sulfate Stimulates Angiogenesis by Regulating Reactive Oxygen Species Production via CYP1B1
- Digital microvascular reactivity does not decline with impaired renal function in chronic kidney disease
- Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma
- The gut microbiota and its relationship with chronic kidney disease
- Decreased ω-6:ω-3 PUFA ratio attenuates ethanol-induced alterations in intestinal homeostasis, microbiota, and liver injury[S]
- Mechanisms of Vascular Calcification in Kidney Disease.
- Evaluation of injury degree of adriamycin-induced nephropathy in rats based on serum metabolomics combined with proline marker.