Formyl peptide receptor 1 suppresses gastric cancer angiogenesis and growth by exploiting inflammation resolution pathways
Explore this paper's citation graph
Summary
It is demonstrated that genetic or pharmacologic modulation of FPR1 in GC cells regulated ALOX5/15 expression and production of the SPMs Resolvin D1 (RvD1) and Lipoxin B4 (LXB4), indicating that FPR 1 and/or pro-resolving pathway components might be used as risk/prognostic markers for GC; ω-6/3-enriched diets, and targeting F PR1 or SPM machinery
- Type
- article
- Published
- 2017-02-21
- Cited by
- 49
- References
- 53
- Access
- Open access
- OpenAlex
- https://openalex.org/W28507800
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3402021
Keywords
Humanities, Philosophy
References
- Resolvin E1 Regulates Inflammation at the Cellular and Tissue Level and Restores Tissue Homeostasis In Vivo1
- Docosahexaenoic acid (DHA) induces apoptosis in human hepatocellular carcinoma cells.
- Role of intracellular and extracellular annexin A1 in migration and invasion of human pancreatic carcinoma cells
- Chronic Inflammation and the Development of Malignancy In the GI Tract
- Formyl Peptide receptor 1 expression is associated with tumor progression and survival in gastric cancer.
- Formyl peptide receptors at the interface of inflammation, angiogenesis and tumor growth.
- Cell proliferation, apoptosis and accumulation of lipid droplets in U937-1 cells incubated with eicosapentaenoic acid.
- Lipoxin A(4) analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: a role for cyclooxygenase-2 and lipoxins in periodontal disease.
- The tumor microenvironment at a glance
- Deficiency of Formyl Peptide Receptor 1 and 2 Is Associated with Increased Inflammation and Enhanced Liver Injury after LPS-Stimulation
- Resolution of inflammation: targeting GPCRs that interact with lipids and peptides
- Defective Gi Protein Coupling in Two Formyl Peptide Receptor Mutants Associated with Localized Juvenile Periodontitis*
- Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis
- Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.
- Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists.
- 15-Lipoxygenases in cancer: a double-edged sword?
- Annexin 1 released by necrotic human glioblastoma cells stimulates tumor cell growth through the formyl peptide receptor 1.
- Discovery of a second 15S-lipoxygenase in humans.
- 5-Lipoxygenase Metabolite 4-HDHA Is a Mediator of the Antiangiogenic Effect of ω-3 Polyunsaturated Fatty Acids
- Toll-like receptors and cancer
Cited by
- New perspectives in cancer: Modulation of lipid metabolism and inflammation resolution
- Glucose impairs tamoxifen responsiveness modulating connective tissue growth factor in breast cancer cells
- The microRNA regulatory landscape of MSC-derived exosomes: a systems view
- Expression and Functions of Formyl Peptide Receptor 1 in Drug-Resistant Bladder Cancer
- Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators.
- Anti‐cancer and analgesic effects of resolvin D2 in oral squamous cell carcinoma
- Targeting lipid mediators in cancer biology
- Peptide Hp(2–20) accelerates healing of TNBS-induced colitis in the rat
- Annexin A12–26 Treatment Improves Skin Heterologous Transplantation by Modulating Inflammation and Angiogenesis Processes
- Aspirin-triggered proresolving mediators stimulate resolution in cancer
- AXL Is a Novel Predictive Factor and Therapeutic Target for Radioactive Iodine Refractory Thyroid Cancer
- A Ganoderma-Derived Compound Exerts Inhibitory Effect Through Formyl Peptide Receptor 2
- The Role of Formyl Peptide Receptor 1 Gene Polymorphisms in Human Colorectal Cancer
- Bioactive lipids, inflammation and chronic diseases.
- Carcinogenesis: Failure of resolution of inflammation?
- A cell-autonomous PD-1/PD-L1 circuit promotes tumorigenicity of thyroid cancer cells by activating a SHP2/Ras/MAPK signalling cascade
- Application of small molecule FPR1 antagonists in the treatment of cancers
- PD-1 blockade delays tumor growth by inhibiting an intrinsic SHP2/Ras/MAPK signalling in thyroid cancer cells
- The G-Protein Coupled Formyl Peptide Receptors and Their Role in the Progression of Digestive Tract Cancer
- Development of a prognostic model based on an immunogenomic landscape analysis of medulloblastoma
Related papers
No related papers recorded.