Interrogating IDH Mutation in Brain Tumor: Magnetic Resonance and Hyperpolarization
Explore this paper's citation graph
Summary
Clinical studies and practical considerations of MRS and hyperpolarized MRS are reviewed, as well as some promising preclinicalhyperpolarization studies to interrogate real-time metabolism in IDH mutations in vivo are discussed.
- Type
- article
- Published
- 2017-02-01
- Cited by
- 5
- References
- 20
- Access
- Open access
- OpenAlex
- https://openalex.org/W28079713
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7567340
Keywords
Primary care, Mental health, Medicine, Primary health care, Mental health care
References
- Automatic quantitation of localized in vivo 1H spectra with LCModel
- Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α
- Detection of 2-Hydroxyglutarate in IDH-mutated Glioma Patients by Spectral-editing and 2D Correlation Magnetic Resonance Spectroscopy
- Non-invasive in vivo assessment of IDH1 mutational status in glioma
- 1H and 13C NMR study of 2‐hydroxyglutaric acid and its lactone
- Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1-13C]pyruvate and 13C magnetic resonance spectroscopic imaging
- 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated glioma patients
- Metabolite Kinetics in C6 Rat Glioma Model Using MRSI of Hyperpolarized [1-13C]Pyruvate
- BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1
- Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma
- Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.
- Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells
- Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors.
- Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma.
- Hyperpolarized 13C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring
- Non-invasive detection of 2-hydroxyglutarate in IDH-mutated gliomas using two-dimensional localized correlation spectroscopy (2D L-COSY) at 7 Tesla
- Interrogating Metabolism in Brain Cancer
- Using thematic analysis in psychology
- Health, United States, 2011: With Special feature on Socioeconomic Status and Health
- IDH1 and IDH2 mutations in gliomas.
Cited by
- Reliable diagnosis of IDH-mutant glioblastoma by 2-hydroxyglutarate detection: a study by 3-T magnetic resonance spectroscopy
- Advances and Challenges in Assessing 2-Hydroxyglutarate in Gliomas by Magnetic Resonance Spectroscopy: A Short Review
- Measuring the Metabolic Evolution of Glioblastoma throughout Tumor Development, Regression, and Recurrence with Hyperpolarized Magnetic Resonance
- In vivo brain MR spectroscopy in gliomas: clinical and pre-clinical chances
- Magnetic Resonance Imaging of Primary Adult Brain Tumors: State of the Art and Future Perspectives
Related papers
- Integration of Mental and Behavioral Health in Pediatric Health Care Clinics
- Knowledge of and Attitudes Toward Mental Illness Among Primary Care Providers in Saint Vincent and the Grenadines
- Health care practitioners' perceptions of public mental health care in the Eastern Cape, South Africa
- Technology Use in Rural Appalachia: A Pilot Study of the Implications for Pediatric Behavioral Health
- 2.47 MENTAL HEALTH AND SUBSTANCE USE SCREENING AND TREATMENT PRACTICES IN COLORADO’S SCHOOL-BASED HEALTH CENTERS
- The association between enrollment in Maryland’s behavioral health homes and outpatient mental health service utilization
- Barriers and facilitators to mental health help-seeking among older adults in The Villages, Florida: A Qualitative Study
- Mental health care of black clients in two types of healthcare organizations