Light-induced oxidation of the telomeric G4 DNA in complex with Zn(II) tetracarboxymethyl porphyrin
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Summary
It is shown that Zn(II) 5,10,15,20-tetrakis(N-carboxymethyl-4-pyridinium)porphyrin (ZnP1) interacts with different conformations of the telomeric sequence d(TAGGG(TTAGGG)3) at submicromolar concentrations without any detectible disturbance of the particular fold.
- Type
- article
- Published
- 2016-10-23
- Cited by
- 24
- References
- 41
- Access
- Open access
- OpenAlex
- https://openalex.org/W27915287
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4406830
Keywords
Porous medium, Hydrate, Clathrate hydrate, Porosity, Chemistry
References
- 8‐Oxoguanine in a quadruplex of the human telomere DNA sequence
- Substitution of adenine for guanine in the quadruplex-forming human telomere DNA sequence G(3)(T(2)AG(3))(3).
- Interactions of TMPyP4 and TMPyP2 with Quadruplex DNA. Structural Basis for the Differential Effects on Telomerase Inhibition
- Structural basis for binding of porphyrin to human telomeres.
- Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
- Measured and calculated CD spectra of G-quartets stacked with the same or opposite polarities.
- Concentration-dependent structural transitions of human telomeric DNA sequences.
- Quadruplexes of human telomere dG(3)(TTAG(3))(3) sequences containing guanine abasic sites.
- Site-specific probing of oxidative reactivity and telomerase function using 7,8-dihydro-8-oxoguanine in telomeric DNA.
- Preferential DNA photocleavage potency of Zn(II) over Ni(II) derivatives of carboxymethyl tetracationic porphyrin: the role of the mode of binding to DNA
- Structure of human telomeric DNA in crowded solution.
- The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo.
- Complexes of antiparallel telomeric G-quadruplex d(TTAGGG)4 with carboxymethyl tetracationic porphyrins
- The role of carboxymethyl substituents in the interaction of tetracationic porphyrins with DNA
- Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex.
- G-Quadruplex Folds of the Human Telomere Sequence Alter the Site Reactivity and Reaction Pathway of Guanine Oxidation Compared to Duplex DNA
- The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures
- A survey of telomerase activity in human cancer.
- Thermochemistry of solution of some quaternized derivatives of tetra(4-pyridyl)porphine in water
- Shedding light on the interaction between TMPyP4 and human telomeric quadruplexes.
Cited by
- In What Ways Do Synthetic Nucleotides and Natural Base Lesions Alter the Structural Stability of G-Quadruplex Nucleic Acids?
- Design, Synthesis and Biological Evaluation of New Substituted Diquinolinyl-Pyridine Ligands as Anticancer Agents by Targeting G-Quadruplex
- Conformational features of intramolecular G4-DNA constrained by single-nucleotide loops.
- Binding and Beyond: What Else Can G-Quadruplex Ligands Do?
- Topologies of G-quadruplex: Biological functions and regulation by ligands.
- Targeting G-quadruplex structures with Zn(II) terpyridine derivatives: a SAR study.
- Photosensitizers Based on G-Quadruplex Ligand for Cancer Photodynamic Therapy
- G-quadruplexes: a promising target for cancer therapy
- Proteins from the DNA Damage Response: Regulation, Dysfunction, and Anticancer Strategies
- Porphyrin Binding and Irradiation Promote G-Quadruplex DNA Dimeric Structure.
- The potential interplay between G-quadruplex and p53: their roles in regulation of ferroptosis in cancer
- Photo-induced telomeric DNA damage in human cancer cells
- Crosstalk between G-quadruplex and ROS
- Mechanisms of Phototoxic Effects of Cationic Porphyrins on Human Cells In Vitro
- NIR C-Myc Pu22 G-quadruplex probe as a photosensitizer for bioimaging and antitumor study.
- Stability of Human Telomeric G-Quadruplexes Complexed with Photosensitive Ligands and Irradiated with Visible Light
- G-quadruplexes and associated proteins in aging and Alzheimer’s disease
- Oxidative Probing of the G4 DNA Structure by Znp1 Porphyrin within Sequences of MYC and TERT Promotors
- Novel phenanthrene imidazoles as telomeric G-quadruplex ligands trigger potent immunogenic cell death in triple-negative breast cancer.
- Quenching of G4-DNA intrinsic fluorescence by ligands
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