Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells
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Summary
Human pluripotent stem cells (hPSCs) derived pituitary cells show basal and stimulus-induced hormone release in vitro and engraftment and hormones release in vivo after transplantation into a murine model of hypopituitarism.
- Type
- article
- Published
- 2016-06-14
- Cited by
- 59
- References
- 46
- Access
- Open access
- OpenAlex
- https://openalex.org/W27304916
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14036996
Keywords
Computer science
References
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- Birthdating Studies Reshape Models for Pituitary Gland Cell Specification
- Scalable human ES culture for therapeutic use: propagation, differentiation, genetic modification and regulatory issues
- Functional transplantation of the rat pituitary gland.
- A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins.
- Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
- Identification of Compounds that Rescue IKBKAP Expression in Familial Dysautonomia-iPS Cells
- Making a Pituitary Gland in a Dish
Cited by
- Regulation of Pituitary Stem Cells by Epithelial to Mesenchymal Transition Events and Signaling Pathways
- CNS disease models with human pluripotent stem cells in the CRISPR age.
- Bringing Neural Cell Therapies to the Clinic: Past and Future Strategies
- Combined small-molecule inhibition accelerates the derivation of functional, early-born, cortical neurons from human pluripotent stem cells
- Pituitary stem cell regulation: who is pulling the strings?
- A MODULAR PLATFORM FOR DIFFERENTIATION OF HUMAN PSCS INTO ALL MAJOR ECTODERMAL LINEAGES
- The role of Glypican 4 during mouse brain development
- Basic Research Advances on Pituitary Stem Cell Function and Regulation
- Molecular Mechanisms Governing Embryonic Differentiation of Pituitary Somatotropes.
- The Processes of Anterior Pituitary Hormone Pulse Generation
- Regulation of Pituitary Progenitor Differentiation by &bgr;-Catenin
- Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection
- Organoids from pituitary as a novel research model toward pituitary stem cell exploration.
- Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
- All Together Now: Modeling the Interaction of Neural With Non-neural Systems Using Organoid Models
- Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation of pituitary progenitor cells.
- Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells.
- Organoid technology for tissue engineering
- Pituitary tumors and immortalized cell lines generated by cre-inducible expression of SV40 T antigen.
- Recent Progress in Stem Cell Research of the Pituitary Gland and Pituitary Adenoma
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