Excessive intimal hyperplasia in human coronary arteries before intimal lipid depositions is the initiation of coronary atherosclerosis and constitutes a therapeutic target.
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Summary
It is suggested that coronary atherosclerosis starts with pathological intimal expansion, resulting in intimal hypoxia and neovascularization from adventitial vasa vasorum, facilitating lipoprotein extraction by previously avascular deep intimal tissues.
- Type
- article
- Published
- 2016-10-01
- Cited by
- 46
- References
- 292
- Access
- Open access
- OpenAlex
- https://openalex.org/W27265770
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19877609
Keywords
Microscopy, Fluorescence microscope, Fluorescence, Materials science, Chemistry
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