The effects of MEK1/2 inhibition on cigarette smoke exposure-induced ET receptor upregulation in rat cerebral arteries.
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Summary
Treatment with MEK1/2 pathway inhibitor offsets SHS exposure-induced ETA receptor upregulation in rat cerebral arteries, and results show the urine cotinine levels from SHS Exposure group were significantly higher than those from the fresh group.
- Type
- article
- Published
- 2016-08-01
- Cited by
- 13
- References
- 34
- OpenAlex
- https://openalex.org/W27212444
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1008339
Keywords
Geography
References
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- Secondhand cigarette smoke exposure causes upregulation of cerebrovascular 5‐HT1B receptors via the Raf/ERK/MAPK pathway in rats
- Vascular plasticity in cerebrovascular disorders
- Cerebral Ischemia Upregulates Vascular Endothelin ETB Receptors in Rat
- Determination of urinary and salivary cotinine using gas and liquid chromatography and enzyme-linked immunosorbent assay.
- Increased sensitivity to ET‐1 in rat cerebral arteries following organ culture
- Subarachnoid Hemorrhage Enhances Endothelin Receptor Expression and Function in Rat Cerebral Arteries
- Endothelium-derived hyperpolarizing factor in vascular physiology and cardiovascular disease.
- Therapeutic Potential of Endothelin Receptor Antagonists in Experimental Stroke
- Cigarette Smoke Upregulates Rat Coronary Artery Endothelin Receptors In Vivo
- Lipid soluble smoke particles upregulate endothelin receptors in rat basilar artery.
- Endothelin Levels Increase in Rat Focal and Global Ischemia
- Up-regulation of RAGE and S100A6 in rats exposed to cigarette smoke.
- Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway
- Gene expression profiling in the human middle cerebral artery after cerebral ischemia
Cited by
- Homocysteine up-regulates endothelin type A receptor in vascular smooth muscle cells through Sirt1/ERK1/2 signaling pathway.
- Tail vein injection of mmLDL upregulates mouse mesenteric artery ETB receptors via activation of the ERK1/2 pathway.
- Role of endothelin‑1 and its receptors in cerebral vasospasm following subarachnoid hemorrhage.
- Enhanced Endothelin A and B Receptor Expression and Receptor-Mediated Vasoconstriction in Rat Mesenteric arteries after Lipopolysaccharide Challenge
- Secondhand cigarette smoke induces increased expression of contractile endothelin receptors in rat coronary arteries via a MEK1/2 sensitive mechanism
- Chronic real-time particulate matter exposure causes rat pulmonary arteriole hyperresponsiveness and remodeling: The role of ETBR-ERK1/2 signaling.
- Nicotine and Vascular Dysfunction
- Smoking and the Pathophysiology of Peripheral Artery Disease
- Airway exposure to urban aerosolized PM2.5 particles induces neuroinflammation and endothelin-mediated contraction of coronary arteries in adult rats
- DMSO-soluble smoking particles up-regulates the vascular endothelin receptors through AMPK-SIRT1 and MAPK pathways.
- PM10 exposure induces bronchial hyperresponsiveness by upreguating acetylcholine muscarinic 3 receptor.
- Major PM2.5 components promote intracranial aneurysm via TP53: Insights from a comprehensive network analysis.
- Doxorubicin increases G-protein coupled receptor-mediated vasoconstriction in coronary arteries via the mitogen-activated protein kinase kinase 1/2 pathway.
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