Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2
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Summary
It is indicated that Ezh2 is essential to sustain tissue integrity and to set up proper maternal mRNA contribution and presents a novel and powerful tool to study how PcG proteins contribute to early vertebrate development.
- Type
- article
- Published
- 2016-05-05
- Cited by
- 30
- References
- 75
- Access
- Open access
- OpenAlex
- https://openalex.org/W27145952
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17174283
Keywords
Successor cardinal, Library science, Extant taxon, Presidency, National library
References
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- The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation
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- The Polycomb group protein Ring1b is essential for pectoral fin development
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- The Polycomb Group Protein Ring1b/Rnf2 Is Specifically Required for Craniofacial Development
- H3K27me and PRC2 transmit a memory of repression across generations and during development
- Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis
- A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos.
- Expression of a vas::EGFP transgene in primordial germ cells of the zebrafish.
Cited by
- Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation
- The histone lysine methyltransferase Ezh2 is required for maintenance of the intestine integrity and for caudal fin regeneration in zebrafish.
- Gene expression profile of a selection of Polycomb Group genes during zebrafish embryonic and germ line development
- Genetic and epigenetic regulation of zebrafish intestinal development
- The ezh2(sa1199) mutant zebrafish display no distinct phenotype
- Loss of the Polycomb group protein Rnf2 results in derepression of tbx-transcription factors and defects in embryonic and cardiac development
- Ezh1 arises from Ezh2 gene duplication but its function is not required for zebrafish development
- Epigenetic gene regulation during zebrafish development: The function of the Polycomb group protein Ezh2 in zebrafish
- Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
- Evolved for success in novel environments: The round goby genome
- Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan
- PRC2 functions in development and congenital disorders
- The round goby genome provides insights into mechanisms that may facilitate biological invasions
- Chemical Genetics Screen Identifies Epigenetic Mechanisms Involved in Dopaminergic and Noradrenergic Neurogenesis in Zebrafish
- Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish
- The Polycomb Orthologues in Teleost Fishes and Their Expression in the Zebrafish Model
- Chromatin dynamics at the maternal to zygotic transition: recent advances from the zebrafish model
- Enhancer of Zeste Homolog 2 (Ezh2) is essential for patterning of multiple musculoskeletal tissues but dispensable for tendon differentiation
- Zebrafish Polycomb repressive complex-2 critical roles are largely Ezh2- over Ezh1-driven and concentrate during early embryogenesis
- Pcgf1 Regulates Early Neural Tube Development Through Histone Methylation in Zebrafish
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