Assembly of a processive messenger RNA polyadenylation complex.

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Summary

Analysis of RNA‐protein interactions by non‐denaturing gel electrophoresis shows that CPSF, PAB II andpoly(A) polymerase form a quaternary complex with the substrate RNA that transiently stabilizes the binding of poly(A), polymerase to the RNA 3′‐end.

Type
article
Published
1993-02-01
Cited by
237
References
1
Access
Open access

Keywords

Polyadenylation, Cleavage and polyadenylation specificity factor, Biology, Antitermination, RNA polymerase II

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