Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes
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Summary
Normal variation in these genes contributes to the continuum of autistic phenotypes, and the brain‐expressed miR‐181 species emerged as potential “umbrella regulator”.
- Type
- article
- Published
- 2015-11-26
- Cited by
- 45
- References
- 78
- Access
- Open access
- OpenAlex
- https://openalex.org/W26612855
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16524860
Keywords
Computer science, Environmental science
References
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- Brief Report: Altered Social Behavior in Isolation-Reared Fmr1 Knockout Mice
- Autism Profiles of Males with Fragile X Syndrome
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Cited by
- Novel candidate genes and variants underlying autosomal recessive neurodevelopmental disorders with intellectual disability
- Sustained lentiviral-mediated overexpression of microRNA124a in the dentate gyrus exacerbates anxiety- and autism-like behaviors associated with neonatal isolation in rats.
- OTTO: a new strategy to extract mental disease-relevant combinations of GWAS hits from individuals
- Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain
- Fragile X related protein 1 (FXR1P) regulates proliferation of adult neural stem cells
- The interaction of GSK3B and FXR1 genotypes may influence the mania and depression dimensions in mood disorders.
- Evolution, immunity and the emergence of brain superautoantigens
- MicroRNAs as biomarkers for psychiatric disorders with a focus on autism spectrum disorder: Current progress in genetic association studies, expression profiling, and translational research
- EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons
- HDAC1 links early life stress to schizophrenia-like phenotypes
- A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms
- Fragile X granules are a family of axonal ribonucleoprotein particles with circuit-dependent protein composition and mRNA cargos
- Sexual dimorphism of AMBRA1-related autistic features in human and mouse
- Functional changes of AMPA responses in human induced pluripotent stem cell–derived neural progenitors in fragile X syndrome
- Regulation of Adult Neurogenesis by the Fragile X Family of RNA Binding Proteins
- Excitation-inhibition dysbalance as predictor of autistic phenotypes.
- Are FXR Family Proteins Integrators of Dopamine Signaling and Glutamatergic Neurotransmission in Mental Illnesses?
- Looking through autistic features in schizophrenia using the PANSS Autism Severity Score (PAUSS).
- The FXR2P low complexity domain drives assembly of multiple fibril types with differing ribosome association in neurons
- Comparative Behavioral Phenotypes of Fmr1 KO, Fxr2 Het, and Fmr1 KO/Fxr2 Het Mice
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