Effects of Phospholipid Composition on the Transfer of a Small Cationic Peptide Across a Model Biological Membrane.
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Summary
The study reveals that protonated lysine residues can be buried further inside an ether lipid membrane than an ester lipid membrane, while branched lipids are found to stabilize less the charged form compared to their unbranched lipid chain counterparts.
- Type
- article
- Published
- 2013-11-23
- Cited by
- 25
- References
- 74
- OpenAlex
- https://openalex.org/W26592298
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44996160
Keywords
Computer science
References
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- Synthesis, structural characterization, and immunological properties of carbon nanotubes functionalized with peptides.
- Molecular Dynamics Study on the Effect of Chain Branching on the Physical Properties of Lipid Bilayers: Structural Stability
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- A Role for Weak Electrostatic Interactions in Peripheral Membrane Protein Binding
- Diffusive Models of Membrane Permeation with Explicit Orientational Freedom.
- Generalized Langevin Methods for Calculating Transmembrane Diffusivity.
- Permeation of the three aromatic dipeptides through lipid bilayers: Experimental and computational study.
- Sequence-Dependent Interfacial Adsorption and Permeation of Dipeptides across Phospholipid Membranes.
- Insight into the interactions, residue snorkeling, and membrane disordering potency of a single antimicrobial peptide into different lipid bilayers
- Effects of hydration on the protonation state of a lysine analog crossing a phospholipid bilayer - insights from molecular dynamics and free-energy calculations.
- Nanoparticle transport across model cellular membranes: when do solubility-diffusion models break down?
- Multiscale Simulations of Biological Membranes: The Challenge To Understand Biological Phenomena in a Living Substance
- Partition of Positively and Negatively Charged Tryptophan Ions in Membranes with Inverted Phospholipid Heads: Simulations and Experiments
- Calculation of apparent pKa values of saturated fatty acids with different lengths in DOPC phospholipid bilayers.
- Anionic nanoparticle-lipid membrane interactions: the protonation of anionic ligands at the membrane surface reduces membrane disruption
- Dynamic Protonation Dramatically Affects the Membrane Permeability of Drug-like Molecules
- New insights on the role of ROS in the mechanisms of sonoporation-mediated gene delivery.
- The Interaction of Camptothecin with Model Cellular Membranes.
- Unassisted N-acetyl-phenylalanine-amide transport across membrane with varying lipid size and composition: kinetic measurements and atomistic molecular dynamics simulation
- On the permeability of cell membranes subjected to lipid oxidation
- Diptool—A Novel Numerical Tool for Membrane Interactions Analysis, Applying to Antimicrobial Detergents and Drug Delivery Aids
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