The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM
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Summary
The ability of forSkolin to maintain the killing of MM cells even at lower concentrations of the conventional agents suggests that forskolin may be used to diminish treatment-associated side effects.
- Type
- article
- Published
- 2015-08-26
- Cited by
- 31
- References
- 60
- Access
- Open access
- OpenAlex
- https://openalex.org/W26306624
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15637692
Keywords
Computer science
References
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Cited by
- Isoforskolin and forskolin attenuate lipopolysaccharide‐induced inflammation through TLR4/MyD88/NF‐κB cascades in human mononuclear leukocytes
- The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is It Time?
- Forskolin sensitizes pancreatic cancer cells to gemcitabine via Stat3 and Erk1/2 inhibition
- GPER promotes tamoxifen-resistance in ER+ breast cancer cells by reduced Bim proteins through MAPK/Erk-TRIM2 signaling axis.
- Natriuretic peptide receptor 2 (NPR2) localized in bovine oocyte underlies a unique mechanism for C-type natriuretic peptide (CNP)-induced meiotic arrest.
- 1,2,3,4,6-Penta-O-Galloyl-Beta-D-Glucopyranoside Inhibits Proliferation of Multiple Myeloma Cells Accompanied with Suppression of MYC Expression
- Active enhancer and chromatin accessibility landscapes chart the regulatory network of primary multiple myeloma.
- Forskolin improves sensitivity to doxorubicin of triple negative breast cancer cells via Protein Kinase A‐mediated ERK1/2 inhibition
- Combination treatment of bisphosphonate (pamidronate) and Quercus infectoria semi- purified fraction promotes proliferation and differentiation of osteoblast cell via expression of Osterix and Runx2 marker
- Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2/3 Demethylases GSKJ4 Inhibitor via Protein Kinase A
- Cytochrome P450 enzymes: A driving force of plant diterpene diversity.
- Forskolin exerts anticancer roles in non-Hodgkin’s lymphomas via regulating Axin/β-catenin signaling pathway
- Molecular mechanisms contributing to glucocorticoid resistance in lymphoid malignancies
- Isoforskolin Inhibits Lipopolysaccharide Activation of the TLR4/MyD-88/NF-κB Pathway in Small Airway Epithelial Cells
- cAMP induces cell apoptosis in multiple myeloma and overcomes bortezomib resistance.
- Blame the signaling: role of cAMP for the resolution of inflammation.
- Latest perspectives on glucocorticoid-induced apoptosis and resistance in lymphoid malignancies.
- Supplementation of c-type natriuretic peptide during in vitro growth period benefits the development of murine preantral follicles
- Supplementation of c-type natriuretic peptide during the whole in vitro growth period benefits the development of murine secondary follicles
- Reprogramming Cancer Stem-like Cells with Nanoforskolin Enhances the Efficacy of Paclitaxel in Targeting Breast Cancer.
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