MicroRNA-Let-7a regulates the function of microglia in inflammation.

Keywords

Microglia, Biology, Inflammation, microRNA, Cell biology

References

• Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor.Alberto Lasa Zulueta — 1998
• IL-4-Induced Selective Clearance of Oligomeric β-Amyloid Peptide1–42 by Rat Primary Type 2 Microglia1Eisuke Shimizu, Kohichi Kawahara, Makoto Kajizono — 2008
• Neuroprotective role of IL-4 against activated microglia.Chien‐Chung Chao, Thomas W. Molitor, S. Hu — 1993
• Activated microglia mediate neuronal cell injury via a nitric oxide mechanism.C C Chao, S Hu, Thomas W. Molitor — 1992
• Acid‐sensing ion channels promote the inflammation and migration of cultured rat microgliaXiaowei Yu, Zhuang‐Li Hu, Ming Ni — 2015
• Extracellular Signal-Regulated Kinase and p38 Subgroups of Mitogen-Activated Protein Kinases Regulate Inducible Nitric Oxide Synthase and Tumor Necrosis Factor-α Gene Expression in Endotoxin-Stimulated Primary Glial CulturesNarayan R. Bhat, Peisheng Zhang, John C. Lee — 1998
• Integrated Expression Profiles of mRNA and miRNA in Polarized Primary Murine MicrogliaRobert W. Freilich, Maya E. Woodbury, Tsuneya Ikezu — 2013
• Microglial Phagocytosis Induced by Fibrillar β-Amyloid and IgGs Are Differentially Regulated by Proinflammatory CytokinesJessica Koenigsknecht-Talboo, Gary E. Landreth — 2005
• Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?Witold Filipowicz, Suvendra N. Bhattacharyya, Nahum Sonenberg — 2008
• M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelinationVéronique E. Miron, Amanda Boyd, Jingwei Zhao — 2013
• Activated Microglia Contribute to the Maintenance of Chronic Pain after Spinal Cord InjuryBryan C. Hains, Stephen G. Waxman — 2006
• EXPRESSION OF SUPPRESSOR OF CYTOKINE SIGNALING (SOCS) GENES IN HUMAN ELDERLY AND ALZHEIMER’S DISEASE BRAINS AND HUMAN MICROGLIADouglas G. Walker, Alexis Whetzel, Lih‐Fen Lue — 2014
• MicroRNA-92a Negatively Regulates Toll-like Receptor (TLR)-triggered Inflammatory Response in Macrophages by Targeting MKK4 Kinase*Lihua Lai, Yinjing Song, Yang Liu — 2013
• Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas.Guoying Mu, Han Liu, Fang Zhou — 2010
• Effects of let-7 microRNA on Cell Growth and Differentiation of Papillary Thyroid Cancer.Jølio Cezar Marques, Ricarte-Filho, César Seigi Fuziwara — 2009
• Protective effects of an anti‐inflammatory cytokine, interleukin‐4, on motoneuron toxicity induced by activated microgliaWeihua Zhao, Wenjie Xie, Qin Xiao — 2006
• Activation of microglial cells by β-amyloid protein and interferon-γLucia Meda, Marco A. Cassatella, Györgyi I. Szendrei — 1995
• Up-Regulation of P2X4 Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic PainLauriane Ulmann, Jon P. Hatcher, Jane P. Hughes — 2008
• Microglia: active sensor and versatile effector cells in the normal and pathologic brainUwe‐Karsten Hanisch, Helmut Kettenmann — 2007
• The let-7 family of microRNAs.Sarah F. Roush, Frank J. Slack — 2008

Cited by

• The biphasic function of microglia in ischemic strokeYuanyuan Ma, Jixian Wang, Yongting Wang — 2017
• Let-7a gene knockdown protects against cerebral ischemia/reperfusion injuryXinmei Jiang, Xuefan Yu, Zhong‐Kun Wang — 2016
• Oxidative stress and pro-inflammatory cytokines may act as one of the signals for regulating microRNAs expression in Alzheimer's disease.Kedar N. Prasad — 2017
• Let-7a Inhibits T-Cell Proliferation and IFN-γ Secretion by Down-Regulating STAT3 Expression in Patients with PsoriasisXiao-Ping Hu, Qian Xie, Chaofeng Chen — 2017
• Interferon-γ alters the immune-related miRNA expression of microvesicles derived from mesenchymal stem cellsAi-qi Zhao, Hui Xie, Sheng‐Yan Lin — 2017
• miR-Let7A Controls the Cell Death and Tight Junction Density of Brain Endothelial Cells under High Glucose ConditionJuhyun Song, So Ra Yoon, Oh Yoen Kim — 2017
• An update: Epstein-Barr virus and immune evasion via microRNA regulationLielian Zuo, Wenxin Yue, Shujuan Du — 2017
• MicroRNAs: Roles in Regulating NeuroinflammationAndrew D. Gaudet, Laura K. Fonken, Linda R. Watkins — 2018
• MiR‐let‐7a regulates anti‐citrullinated protein antibody‐induced macrophage activation and correlates with the development of experimental rheumatoid arthritisWei Zhu, Jianbo Yu, Shou Qiu — 2017
• Platelet-Enriched MicroRNAs and Cardiovascular HomeostasisAmro Elgheznawy, Ingrid Fleming — 2017
• Redox Regulation and Noncoding RNAsMatthias S. Leisegang, Katrin Schröder, Ralf P. Brandes — 2017
• CNS inflammation and neurodegeneration.Tanuja Chitnis, Howard L. Weiner — 2017
• Comparative analysis of cytokine/chemokine regulatory networks in patients with hippocampal sclerosis (HS) and focal cortical dysplasia (FCD)Arpna Srivastava, Aparna Banerjee Dixit, Debasmita Paul — 2017
• Understanding the role of astrocytes in HIV-1 neuropathogenesis: novel strategies to target astrocyte function and HIV-1 associated neurocognitive disorderRuhee Jain — 2018
• Epigenetic regulation of inflammation in strokeGavin Yong-Quan Ng, Yun-An Lim, Christopher G. Sobey — 2018
• Induction of microRNA-let-7a inhibits lung adenocarcinoma cell growth by regulating cyclin D1Wei Zhao, Jinxia Hu, Ruimin Hao — 2018
• Epigenetics Control Microglia PlasticityMathilde Cheray, Bertrand Joseph — 2018
• MicroRNAs and the Genetic Nexus of Brain Aging, Neuroinflammation, Neurodegeneration, and Brain TraumaSaumyendra N. Sarkar, Ashley E. Russell, Elizabeth B. Engler-Chiurazzi — 2019
• Signature of Aberrantly Expressed microRNAs in the Striatum of Rotenone-Induced Parkinsonian RatsCamila Hillesheim Horst, Franciele Schlemmer, Natália de Aguiar Montenegro — 2018
• MicroRNAs of microglia: wrestling with central nervous system diseaseTianlong Wang, Xiaohua Wang — 2018

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