Determinants of Intestinal Permeability in Healthy First-Degree Relatives of Individuals with Crohn's Disease
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Summary
The LacMan ratio was not found to be significantly heritable suggesting that the contribution of genetic factors to the determination of intestinal permeability in healthy FDRs is modest and environmental factors, such as smoking, are likely more important determinants.
- Type
- article
- Published
- 2015-04-01
- Cited by
- 54
- References
- 43
- Access
- Open access
- OpenAlex
- https://openalex.org/W25734694
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28079978
Keywords
Insulin resistance, Prolactinoma, Insulin, Medicine, Internal medicine
References
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Cited by
- On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death.
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- Inflammatory Bowel Disease in Asia: A Second Chance at Uncovering Environmental Factors
- Use of Humanized Mice to Study the Pathogenesis of Autoimmune and Inflammatory Diseases
- Host-microbiome interaction in Crohn's disease: A familiar or familial issue?
- A Promoter Variant Within the Aryl Hydrocarbon Receptor Gene Is Associated with an Epithelial Barrier Defect in Smokers with Crohn's Disease
- Diet as a Trigger or Therapy for Inflammatory Bowel Diseases.
- Increased Intestinal Permeability in Relatives of Patients With Crohn’s Disease Is Not Associated With Small Bowel Ulcerations
- Challenges for epigenetic research in inflammatory bowel diseases.
- Age and Sex Normalization of Intestinal Permeability Measures for the Improved Assessment of Enteropathy in Infancy and Early Childhood: Results from the MAL-ED Study.
- Host genetic variation and its microbiome interactions within the Human Microbiome Project
- FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects
- Determinants of IBD Heritability: Genes, Bugs, and More.
- The role of diet in the etiopathogenesis of inflammatory bowel disease
- Evolving role of diet in the pathogenesis and treatment of inflammatory bowel diseases
- Retinoic Acid, Leaky Gut, and Autoimmune Diseases
- Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease.
- Association between increased intestinal permeability and disease: A systematic review
- The interplay between microbes and the immune response in inflammatory bowel disease
- The Multifactorial Etiopathogeneses Interplay of Inflammatory Bowel Disease: An Overview