Clinical associations between IL-17 family cytokines and periodontitis and potential differential roles for IL-17A and IL-17E in periodontal immunity
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Summary
Serum IL-17A:IL-17E may be a marker of disease severity and IL-18E may have opposing roles to IL- 17A in periodontitis pathogenesis.
- Type
- article
- Published
- 2014-11-05
- Cited by
- 92
- References
- 51
- Access
- Open access
- OpenAlex
- https://openalex.org/W2124297479
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52805150
Keywords
Periodontitis, Porphyromonas gingivalis, Chronic periodontitis, Interleukin 17, Saliva
References
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- Regulation of IL-9 expression by IL-25 signaling
- Verification of IL-17A and IL-17F in oral tissues and modulation of their expression pattern by steroid hormones.
- Levels of interleukin-17 in gingival crevicular fluid and in supernatants of cellular cultures of gingival tissue from patients with chronic periodontitis.
- Is interleukin-17 involved in the interaction between polycystic ovary syndrome and gingival inflammation?
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- Structure and signalling in the IL-17 receptor superfamily
- MMPs, IL-1, and TNF are Regulated by IL-17 in Periodontitis
- Constitutive and interleukin-1-inducible phosphorylation of p65 NF-kappaB at serine 536 is mediated by multiple protein kinases including IkappaB kinase (IKK)-alpha, IKKbeta, IKKepsilon, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to
- Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut.
- Evaluation of IL17A expression and of IL17A, IL17F and IL23R gene polymorphisms in Brazilian individuals with periodontitis.
- Human periodontal ligament cells facilitate leukocyte recruitment and are influenced in their immunomodulatory function by Th17 cytokine release.
Cited by
- Oral Mucosal Epithelial Cells
- Interactions between HIV, microorganisms and immune humoral factors in HIV-2 and HIV-1 infection
- T cells, teeth and tissue destruction - what do T cells do in periodontal disease?
- Salivary cytokines as biomarkers of periodontal diseases.
- Interleukin-17A Gene Variability in Patients with Type 1 Diabetes Mellitus and Chronic Periodontitis: Its Correlation with IL-17 Levels and the Occurrence of Periodontopathic Bacteria
- The Influences of Periodontal Status and Periodontal Pathogen Quantity on Salivary 8-Hydroxydeoxyguanosine and Interleukin-17 Levels.
- Microbial biofilm composition influences the host immune response
- The effect of periodontal scaling and root polishing on serum IL-17E concentrations and the IL-17A:IL-17E ratio
- Favourable effects of Bacillus subtilis and Bacillus licheniformis on experimental periodontitis in rats.
- Cytokine expression in gingival and intestinal tissues of patients with periodontitis and inflammatory bowel disease: An exploratory study.
- Periodontitis‐associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14+ monocytes leading to enhanced Th17/IL‐17 responses
- Salivary Concentrations of Interleukin (IL)-1β, IL-17A, and IL-23 Vary in Relation to Periodontal Status.
- Biomarkers and Bacteria Around Implants and Natural Teeth in the Same Individuals
- Microbiological and immunological aspects of equine periodontal disease
- The aggravation of arthritis by periodontitis is dependent of IL‐17 receptor A activation
- Periodontal disease and periodontal bacteria as triggers for rheumatoid arthritis.
- Polymorphisms in interleukins 17A and 17F genes and periodontitis: results from a meta-analysis
- Interleukin‐17 family cytokines in protective immunity against infections: role of hematopoietic cell‐derived and non‐hematopoietic cell‐derived interleukin‐17s
- Intraoral versus extraoral cementation of implant‐supported single crowns: Clinical, biomarker, and microbiological comparisons
- Studies on onset and lesion characteristics of periodontitis
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