The Network of Epithelial-mesenchymal transition: potential new targets for tumor resistance

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Summary

This review highlights the potential key therapeutic targets of EMT linked with tumor aggressiveness, hypoxia, angiogenesis and cancer stem cells, emphasizing on an emerging EMT-associated NF-κB/HER2/STAT3 pathway in radioresistance of breast cancer stem Cells.

Type
article
Published
2014-10-01
Cited by
136
References
217
Access
Open access

Keywords

Materials science, Sintering, Metallurgy

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