Effects of an energy-restricted diet rich in plant-derived α-linolenic acid on systemic inflammation and endothelial function in overweight-to-obese patients with metabolic syndrome traits
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Summary
In overweight-to-obese patients with metabolic syndrome traits, both vascular function and inflammation are improved during body-weight loss, indicating the existence of independent favourable physiological effects of ALA during weight loss.
- Type
- article
- Published
- 2014-09-02
- Cited by
- 56
- References
- 52
- Access
- Open access
- OpenAlex
- https://openalex.org/W2138141860
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6600783
Keywords
Internal medicine, Endocrinology, Overweight, Inflammation, Metabolic syndrome
References
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- YKL-40 is Elevated in Morbidly Obese Patients and Declines After Weight Loss
- Slow desaturation and elongation of linoleic and alpha-linolenic acids as a rationale of eicosapentaenoic acid-rich diet to lower blood pressure and serum lipids in normal, hypertensive and hyperlipemic subjects.
- Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients
- Fish, long-chain omega-3 polyunsaturated fatty acids and prevention of cardiovascular disease--eat fish or take fish oil supplement?
- Omega-3 fatty acids and metabolic syndrome: effects and emerging mechanisms of action.
- The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid.
- The renin-angiotensin system in adipose tissue and its metabolic consequences during obesity.
- YKL-40, a biomarker of inflammation, is elevated in patients with type 2 diabetes and is related to insulin resistance
- Effect of weight loss on inflammatory and endothelial markers and FMD using two low-fat diets
- Reduction of Inflammatory Cytokine Concentrations and Improvement of Endothelial Functions in Obese Women After Weight Loss Over One Year
- High serum YKL-40 concentration is associated with cardiovascular and all-cause mortality in patients with stable coronary artery disease.
- Increased circulating and visceral adipose tissue expression levels of YKL-40 in obesity-associated type 2 diabetes are related to inflammation: impact of conventional weight loss and gastric bypass.
- Serum YKL-40 predicts long-term mortality in patients with stable coronary disease: a prognostic study within the CLARICOR trial.
- Cellular adhesion molecules and cardiovascular disease. Part II. Their association with conventional and emerging risk factors, acute coronary events and cardiovascular risk prediction
- Pre-diabetes, metabolic syndrome, and cardiovascular risk.
- Tumor Necrosis Factor-α and Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome
Cited by
- Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches.
- No Positive Influence of Ingesting Chia Seed Oil on Human Running Performance
- Is there A Role for Alpha-Linolenic Acid in the Fetal Programming of Health?
- Targeting vascular (endothelial) dysfunction
- Association of endothelial proliferation with the magnitude of weight loss during calorie restriction
- Metabolism and functional effects of plant-derived omega-3 fatty acids in humans.
- Effect of dietary alpha-linolenic acid on blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials
- Moderate Walking Enhances the Effects of an Energy-Restricted Diet on Fat Mass Loss and Serum Insulin in Overweight and Obese Adults in a 12-Week Randomized Controlled Trial.
- Systemic and vascular inflammation in an in-vitro model of central obesity
- Rapid Weight Loss vs. Slow Weight Loss: Which is More Effective on Body Composition and Metabolic Risk Factors?
- Effects of a hypoenergetic diet rich in α-linolenic acid on fatty acid composition of serum phospholipids in overweight and obese patients with metabolic syndrome.
- The effects of omega-3 supplementation on whole body and skeletal muscle energy metabolism in humans
- Omega-3 polyunsaturated fatty acids-enriched hen eggs consumption enhances microvascular reactivity in young healthy individuals.
- An Overview of Novel Dietary Supplements and Food Ingredients in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease
- A brief review of physiological roles, plant resources, synthesis, purification and oxidative stability of Alpha-linolenic Acid
- Effect of alpha-linolenic acid in combination with the flavonol quercetin on markers of cardiovascular disease risk in healthy, non-obese adults: A randomized, double-blinded placebo-controlled crossover trial.
- Comparative Transcriptome Analysis Reveals an Efficient Mechanism for α-Linolenic Acid Synthesis in Tree Peony Seeds
- Bariatric Surgery: Bad to the Bone, Part 1.
- Omega-3 Polyunsaturated Fatty Acids Inhibit IL-17A Secretion through Decreased ICAM-1 Expression in T Cells Co-Cultured with Adipose-Derived Stem Cells Harvested from Adipose Tissues of Obese Subjects.
- The Evaluation of Cardiovascular Risk Parameters Using Multiplex Immunoassay in Women with Primary Hyperlipiemia and Obese HyperlipidemicWomen
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