Magnesium ions facilitate integrin alpha 2‐ and alpha 3‐mediated proliferation and enhance alkaline phosphatase expression and activity in hBMSCs
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Summary
Exposure to magnesium ions facilitated hBMSC proliferation via integrin α2 and α3 expression and partly promoted differentiation into osteoblasts via the alteration of ALP expression and activity, suggesting magnesium could be a useful biomaterial for orthopaedic applications such as bone implant biomaterials for repair and regeneration of bone defects in orthopedic and dental fields.
- Type
- article
- Published
- 2016-10-01
- Cited by
- 58
- References
- 35
- OpenAlex
- https://openalex.org/W24616281
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10380832
Keywords
Immigration, Development economics, Political science, Nexus (standard), Fertility
References
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- FUNCTIONAL HYPOPARATHYROIDISM AND PARATHYROID HORMONE END‐ORGAN RESISTANCE IN HUMAN MAGNESIUM DEFICIENCY
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Cited by
- The Biocompatibility of Degradable Magnesium Interference Screws: An Experimental Study with Sheep
- Balancing the Osteogenic and Antibacterial Properties of Titanium by Codoping of Mg and Ag: An in Vitro and in Vivo Study.
- Small molecule delivery through nanofibrous scaffolds for musculoskeletal regenerative engineering
- Behavior of bone cells in contact with magnesium implant material.
- A systemic study on key parameters affecting nanocomposite coatings on magnesium substrates.
- Effect of Magnesium and Osteoblast Cell Presence on Hydroxyapatite Formation on (Ti,Mg)N Thin Film Coatings
- Restoring the osteogenic activity of bacterial debris contaminated titanium by doping with magnesium
- Magnesium and osteoarthritis: from a new perspective
- INVESTIGATING THE MECHANISM OF INTRACELLULAR SIGNALING OF MAGNESIUM IN HUMAN BONE MARROW STROMAL CELLS (hBMSCs): POTENTIAL ROLE IN OSTEOGENESIS
- Via precise interface engineering towards bioinspired composites with improved 3D printing processability and mechanical properties.
- Strontium and magnesium ions released from bioactive titanium metal promote early bone bonding in a rabbit implant model.
- Applications of Metals for Bone Regeneration
- Tuning mechanical reinforcement and bioactivity of 3D printed ternary nanocomposites by interfacial peptide-polymer conjugates
- Porous Phosphate-Based Glass Microspheres Show Biocompatibility, Tissue Infiltration, and Osteogenic Onset in an Ovine Bone Defect Model.
- Enhanced osteogenic differentiation of bone mesenchymal stem cells on magnesium-incorporated titania nanotube arrays.
- The osteoinduction of RGD and Mg ion functionalized bioactive zirconia coating
- Effect of magnesium ions/Type I collagen promote the biological behavior of osteoblasts and its mechanism
- In situ gas foaming based on magnesium particle degradation: A novel approach to fabricate injectable macroporous hydrogels.
- Hierarchical Micro-Nano Topography Promotes Cell Adhesion and Osteogenic Differentiation via Integrin α2-PI3K-AKT Signaling Axis
- Soapstone reinforced hydroxyapatite coatings for biomedical applications
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