Zfp322a Regulates Mouse ES Cell Pluripotency and Enhances Reprogramming Efficiency

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Summary

It is reported that Zfp 322a is required for mES cell identity since depletion of Zfp322a directs mES cells towards differentiation, and ZFP322a is found to be a novel reprogramming factor that can replace Sox2 in the classical Yamanaka's factors (OSKM).

Type
article
Published
2014-02-01
Cited by
23
References
58
Access
Open access

Keywords

Reprogramming, Biology, SOX2, Homeobox protein NANOG, Cell biology

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