In vitro and in vivo anti-inflammatory effects of a novel 4,6-bis ((E)-4-hydroxy-3-methoxystyryl)-1-phenethylpyrimidine-2(1H)-thione.
Explore this paper's citation graph
Summary
HPT demonstrated anti-inflammatory activity both in LPS-induced RAW 264.7 cells and TPA-stimulated mouse skin and may therefore serve as a potential anti- inflammation agent.
- Type
- article
- Published
- 2014-01-21
- Cited by
- 11
- References
- 54
- OpenAlex
- https://openalex.org/W24304388
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20521395
Keywords
Computer science
References
- Chemoprevention by isothiocyanates and their underlying molecular signaling mechanisms.
- Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
- Pharmacodynamics and Toxicodynamics of Drug Action: Signaling in Cell Survival and Cell Death
- A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.
- p38 Mitogen-activated Protein Kinase Negatively Regulates the Induction of Phase II Drug-metabolizing Enzymes That Detoxify Carcinogens*
- p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes*
- Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis.
- The synergistic effect
- 6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages.
- Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids.
- Involvement of tumor necrosis factor (TNF)-alpha in phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin edema in mice.
- Inflammation and cancer: An ancient link with novel potentials
- Effects of Selected Ginsenosides on Phorbol Ester‐Induced Expression of Cyclooxygenase‐2 and Activation of NF‐κB and ERK1/2 in Mouse Skin
- Nitric oxide and superoxide in inflammation and immune regulation.
- Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2
- Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair
- Synergistic Effect of Combination of Phenethyl Isothiocyanate and Sulforaphane or Curcumin and Sulforaphane in the Inhibition of Inflammation
- Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia
- Procyanidins from Wild Grape (Vitis amurensis) Seeds Regulate ARE-Mediated Enzyme Expression via Nrf2 Coupled with p38 and PI3K/Akt Pathway in HepG2 Cells
- p38 Mitogen-activated Protein Kinase Down-regulates Nitric Oxide and Up-regulates Prostaglandin E2 Biosynthesis Stimulated by Interleukin-1β*
Cited by
- Anti-Inflammatory Effect of Quercetin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid
- Phytochemical Analysis and Anti-Inflammatory Activity of the Extracts of the African Medicinal Plant Ximenia caffra
- Epigenetic DNA Methylation of Anti-oxidative Stress Regulator NRF2 in Human Prostate Cancer
- The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane- and dextran sulfate sodium-treated CF-1 mice.
- Dual inhibition of nitric oxide and prostaglandin E2 production by polysubstituted 2-aminopyrimidines.
- Anti-inflammatory effects of oroxylin A on RAW 264.7 mouse macrophages induced with polyinosinic-polycytidylic acid
- Corynoline Isolated from Corydalis bungeana Turcz. Exhibits Anti-Inflammatory Effects via Modulation of Nfr2 and MAPKs
- A newly synthesized macakurzin C-derivative attenuates acute and chronic skin inflammation: The Nrf2/heme oxygenase signaling as a potential target.
- Isocassiaoccidentalin B, A New C‐Glycosyl Flavone Containing a 3‐Keto Sugar, and Other Constituents from Cassia nomame
- Emerging epigenetics in cancer chemoprevention by dietary phytochemicals
- In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)6-NH2 and Lau-(Lys-βNspe)6-NH2 Against PMA-Induced Acute Inflammation
Related papers
No related papers recorded.