Impact of Molecular Weight on Lymphatic Drainage of a Biopolymer-Based Imaging Agent
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Summary
The specific lymphatic uptake and increased nodal retention of HA conjugates indicate significant potential for development as a natural biopolymer for intralymphatic drug delivery and imaging.
- Type
- article
- Published
- 2012-05-23
- Cited by
- 38
- References
- 67
- Access
- Open access
- OpenAlex
- https://openalex.org/W24300232
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10513859
Keywords
Computer science
References
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- Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration
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- Noninvasive imaging of quantum dots in mice.
Cited by
- Overcoming transport barriers for interstitial-, lymphatic-, and lymph node-targeted drug delivery
- Lymphatic system: a prospective area for advanced targeting of particulate drug carriers
- CD44-Tropic Polymeric Nanocarrier for Breast Cancer Targeted Rapamycin Chemotherapy
- [Podoconiosis, a society and medical community neglected disease].
- Routes of Administration and Dose Optimization of Soluble Antigen Arrays in Mice with Experimental Autoimmune Encephalomyelitis
- Single-Step Grafting of Aminooxy-Peptides to Hyaluronan: A Simple Approach to Multifunctional Therapeutics for Experimental Autoimmune Encephalomyelitis
- Molecular Dynamics of Multivalent Soluble Antigen Arrays Support a Two-Signal Co-delivery Mechanism in the Treatment of Experimental Autoimmune Encephalomyelitis.
- Antigen-Specific Binding of Multivalent Soluble Antigen Arrays Induces Receptor Clustering and Impedes B Cell Receptor Mediated Signaling.
- Guiding Principles in the Design of Molecular Bioconjugates for Vaccine Applications
- [Podoconiosis, a society and medical community neglected disease].
- Hyaluronan-lysine cisplatin drug carrier for treatment of localized cancers: pharmacokinetics, tolerability, and efficacy in rodents and canines
- Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation
- Engineering Particles and Polymers to Improve Pulmonary Therapeutics
- Optimizing the Treatment of Experimental Autoimmune Encephalomyelitis via Pulmonary Delivery of Soluble Antigen Arrays
- Biodistribution of radiolabeled polyglutamic acid and PEG‐polyglutamic acid nanocapsules
- An Activatable Fluorescent γ-Polyglutamic Acid Complex for Sentinel Lymph Node Imaging.
- Progress and opportunities for enhancing the delivery and efficacy of checkpoint inhibitors for cancer immunotherapy
- Pulmonary Administration of Soluble Antigen Arrays is Superior to Antigen in Treatment of Experimental Autoimmune Encephalomyelitis
- Targeting CpG Adjuvant to Lymph Node via Dextran Conjugate Enhances Antitumor Immunotherapy
- Lymph node metastases: importance of detection and treatment strategies
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