Antibiotic treatment of Pseudomonas aeruginosa biofilms stimulates expression of the magnesium transporter gene mgtE.
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Summary
This work has demonstrated an increase in mgtE transcript levels following antibiotic treatment with most of the 12 antibiotics tested, and observed that AlgR, which regulates production of the biofilm polysaccharide alginate, alters MgtE-mediated cytotoxicity, suggesting that AlGR is involved in linking external inducing signals tomgtE transcription and downstream virulence and biofilm activities.
- Type
- article
- Published
- 2014-01-01
- Cited by
- 20
- References
- 75
- Access
- Open access
- OpenAlex
- https://openalex.org/W24162608
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39712794
Keywords
Art
References
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- Proteomics Analysis Reveals a Potential Antibiotic Cocktail Therapy Strategy for Aeromonas hydrophila Infection in Biofilm.
- Hydrogen containing fuel gas generation from organic wastes using photon activated magnesium metal catalyst
- Molecular mechanisms of cytotoxicity regulation in pseudomonas aeruginosa by the magnedium transporter MGTE
- Pseudomonas aeruginosa Magnesium Transporter MgtE Inhibits Type III Secretion System Gene Expression by Stimulating rsmYZ Transcription
- Yersinia pseudotuberculosis BarA-UvrY Two-Component Regulatory System Represses Biofilms via CsrB
- Phosphoglycerate mutase affects Stenotrophomonas maltophilia attachment to biotic and abiotic surfaces
- RNA-Dependent Regulation of Virulence in Pathogenic Bacteria
- Bacterial Biofilm Eradication Agents: A Current Review
- Biofilm and Virulence Regulation in the Cystic Fibrosis-Associated Pathogens, Stenotrophomonas maltophilia and Pseudomonas aeruginosa
- Sub-minimum inhibitory concentrations of biocides induced biofilm formation in Pseudomonas aeruginosa
- DNA alternate polymerase PolB mediates inhibition of type III secretion in Pseudomonas aeruginosa
- The Pathogenic Yersiniae – Advances in the Understanding of Physiology and Virulence, Volume II
- The Effect of Benzyl Isothiocyanate on the Expression of Genes Encoding NADH Oxidase and Fibronectin-Binding Protein in Oral Streptococcal Biofilms
- Markedly decreased growth rate and biofilm formation ability of Acinetobacter schindleri after a long-duration (64 days) spaceflight.
- Novel Mg 2+ binding sites in the cytoplasmic domain of the MgtE Mg 2+ channels revealed by X-ray crystal structures
- Role of SMF-1 and cbl pili in Stenotrophomonas maltophilia biofilm formation
- The Genus Pseudomonas
- Acidosis Potentiates the Host Proinflammatory Interleukin-1 (cid:2) Response to Pseudomonas aeruginosa Infection
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