Characterisation, cytotoxicity and apoptosis studies of methotrexate-loaded PLGA and PLGA-PEG nanoparticles
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Summary
The cytotoxicity experiment showed that the nanoparticles were more effective than pure MTX and increase the activity of caspase-3 in MCF7 and AGS and A549 cell lines.
- Type
- article
- Published
- 2014-04-16
- Cited by
- 45
- References
- 38
- OpenAlex
- https://openalex.org/W24124881
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:46595610
Keywords
Pace, History, Literature, Art, Art history
References
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- Development and characterization of single step self-assembled lipid polymer hybrid nanoparticles for effective delivery of methotrexate
- Recent trends in preparation of poly(lactide- co -glycolide) nanoparticles by mixing polymeric organic solution with antisolvent
- The Role of Nanoparticle in Brain Permeability: An in-vitro BBB Model
- The ligand (s) anchored lipobrid nanoconstruct mediated delivery of methotrexate: an effective approach in breast cancer therapeutics.
- Methotrexate Nanoparticles Prepared with Codendrimer from Polyamidoamine (PAMAM) and Oligoethylene Glycols (OEG) Dendrons: Antitumor Efficacy in Vitro and in Vivo
- Nanostructured lipid carriers: versatile oral delivery vehicle
- Building the design, translation and development principles of polymeric nanomedicines using the case of clinically advanced poly(lactide(glycolide))-poly(ethylene glycol) nanotechnology as a model: An industrial viewpoint.
- Pharmacokinetic study of furosemide incorporated PLGA microspheres after oral administration to rat
- Development of Albumin Coupled, Cholesterol Stabilized, Lipid Nanoemulsion of Methotrexate, and TNF-α Inhibitor for Improved In Vivo Efficacy Against Rheumatoid Arthritis
- Glucagon-like peptide-1 and glucagon-like peptide-1 analogs nanotechnology-based systems for prevention and therapy of diabetes
- Monitoring structural features, biocompatibility and biological efficacy of gamma-irradiated methotrexate-loaded spray-dried microparticles.
- Ascorbic acid tethered polymeric nanoparticles enable efficient brain delivery of galantamine: An in vitro-in vivo study
- Development and optimization of methotrexate-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery applications.
- Modeling the Accumulation of Degradable Polymer Drug Carriers in the Brain
- Preparation of Methotrexate loaded PLGA nanoparticles coated with PVA and Poloxamer188
- A Comprehensive Physicochemical, In Vitro and Molecular Characterization of Letrozole Incorporated Chitosan-Lipid Nanocomplex
- Exploiting gelatin nanocarriers in the pulmonary delivery of methotrexate for lung cancer therapy
- Preparation and In Vitro/In Vivo Characterization of Polymeric Nanoparticles Containing Methotrexate to Improve Lymphatic Delivery
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