Studies toward the development of new silicon-containing building blocks for the direct (18)F-labeling of peptides.
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Summary
Density functional theory calculations were used to predict the hydrolytic stability of di-tert-butylfluorosilanes 2-23 with the aim to improve the in vivo properties of (18)F-labeled silicon-containing biomolecules.
- Type
- article
- Published
- 2013-09-18
- Cited by
- 28
- References
- 36
- OpenAlex
- https://openalex.org/W23992105
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20398745
Keywords
Art, Humanities
References
- Donorfreie und donorhaltige supersilylalkalimetalle tBu3SiM1: Synthesen, charakterisierung, strukturen
- Peptide radiopharmaceuticals in nuclear medicine
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- Molecular imaging with PET.
- Characterization of high‐affinity receptors for bombesin/gastrin releasing peptide on the human prostate cancer cell lines PC‐3 and DU‐145: Internalization of receptor bound 125I‐(Tyr4) bombesin by tumor cells
- Selective reactions of azide-substituted .alpha.-diazo amides with olefins and alcohols using rhodium(II) catalysts
- Synthesis, 18F-labeling, and in vitro and in vivo studies of bombesin peptides modified with silicon-based building blocks.
- The First Lithium Fluorosilanolate–A Building Block for Directed Siloxane Synthesis
- Toward [18F]-labeled aryltrifluoroborate radiotracers: in vivo positron emission tomography imaging of stable aryltrifluoroborate clearance in mice.
- Organofluorosilanes as model compounds for 18F-labeled silicon-based PET tracers and their hydrolytic stability: experimental data and theoretical calculations (PET = positron emission tomography).
- ELECTRONIC STRUCTURE CALCULATIONS ON WORKSTATION COMPUTERS: THE PROGRAM SYSTEM TURBOMOLE
- Radiolabeled peptides and other ligands for receptors overexpressed in tumor cells for imaging neoplasms.
- A Novel Method of 18F Radiolabeling for PET
- Climbing the density functional ladder: nonempirical meta-generalized gradient approximation designed for molecules and solids.
- Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids.
- The mechanism of solvolysis of β-ketosilanes
- Design of silicon-based misonidazole analogues and (18)F-radiolabelling.
- Fully optimized contracted Gaussian basis sets of triple zeta valence quality for atoms Li to Kr
- A comparative study of N.C.A. fluorine-18 labeling of proteins via acylation and photochemical conjugation.
- Stabilization of diazene in Fe(II)–sulfur model complexes relevant for nitrogenase activity. I. A new approach to the evaluation of intramolecular hydrogen bond energies
Cited by
- Synthesis and in vitro and in vivo evaluation of SiFA-tagged bombesin and RGD peptides as tumor imaging probes for positron emission tomography.
- One-Pot Two-Step Radiosynthesis of a New 18F-Labeled Thiol Reactive Prosthetic Group and Its Conjugate for Insulinoma Imaging
- 18F-Labelled Intermediates for Radiosynthesis by Modular Build-Up Reactions: Newer Developments
- 18F-Labeled Silicon-Based Fluoride Acceptors: Potential Opportunities for Novel Positron Emitting Radiopharmaceuticals
- Enhanced Nucleophilic Fluorination and Radiofluorination of Organosilanes Appended with Potassium-Chelating Leaving Groups
- [(18)F]-Group 13 fluoride derivatives as radiotracers for positron emission tomography.
- Ortho-stabilized 18F-azido click agents and application in PET imaging of single-stranded DNA aptamer
- Review Article 18 F-Labelled Intermediates for Radiosynthesis by Modular Build-Up Reactions: Newer Developments
- In Vivo Evaluation of 18F-SiFAlin–Modified TATE: A Potential Challenge for 68Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET
- From Unorthodox to Established: The Current Status of (18)F-Trifluoroborate- and (18)F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging.
- New strategies for rapid (18)F-radiolabeling of biomolecules for radionuclide-based in vivo imaging.
- Fluorine-18 Radiochemistry, Labeling Strategies and Synthetic Routes
- Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on In Vitro SSTR Binding and In Vivo Pharmacokinetics.
- [18F]-Fluoride capture and release: azeotropic drying free nucleophilic aromatic radiofluorination assisted by a phosphonium borane.
- Alkali Metal-Hydroxide-Catalyzed C(sp)-H Bond silylation.
- Crown Ether Nucleophilic Catalysts (CENCs): Agents for Enhanced Silicon Radiofluorination
- Designing Silylated l-Amino Acids using a Wittig Strategy: Synthesis of Peptide Derivatives and 18F-Labelling
- 18F-Radiolabeling and In Vivo Analysis of SiFA-Derivatized Polymeric Core-Shell Nanoparticles.
- The 4-N-Acyl and 4-N-Alkyl Gemcitabine Analogues with Silicon-Fluoride-Acceptor: Application to 18F-Radiolabeling
- Evaluation of Organo [18F]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers
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