Evidence for the antagonistic form of CXC‐motif chemokine CXCL10 in serous epithelial ovarian tumours
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Summary
It is suggested that CXCL10 cleavage and subsequent antagonism of immune cell recruitment may be a feature of the “immunoreactive” HGSOC subtype, leading to early impairment of the immune response and subsequently worsening patient prognosis.
- Type
- article
- Published
- 2014-02-01
- Cited by
- 43
- References
- 43
- Access
- Open access
- OpenAlex
- https://openalex.org/W23873303
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27086054
Keywords
Palm oil, Rural development, Business, Agricultural economics, Geography
References
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- Incretin agents in type 2 diabetes.
- Matrix Metalloproteinase Processing of CXCL11/I-TAC Results in Loss of Chemoattractant Activity and Altered Glycosaminoglycan Binding*
- Increased adhesion potency of ovarian carcinoma cells to mesothelial cells by overexpression of dipeptidyl peptidase IV
- Expression profiling of dipeptidyl peptidase 8 and 9 in breast and ovarian carcinoma cell lines.
- Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation.
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- The emerging role of CXC chemokines in epithelial ovarian cancer.
- The expression of dipeptidyl peptidase IV (DPPIV/CD26) is associated with enhanced chemosensitivity to paclitaxel in epithelial ovarian carcinoma cells
- Risk of Hepatocellular Carcinoma in Diabetic Patients and Risk Reduction Associated With Anti-Diabetic Therapy: A Population-Based Cohort Study
- Cleavage of chemokines CCL2 and CXCL10 by matrix metalloproteinases-2 and -9: implications for chemotaxis.
Cited by
- Enhancing T-cell responses to vaccination of HIV-1 infected subjects on antiretroviral therapy
- The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis
- Identification of novel dipeptidyl peptidase 9 substrates by two‐dimensional differential in‐gel electrophoresis
- CXCL10 Expression Status is Prognostic in Patients with Advanced Thoracic Esophageal Squamous Cell Carcinoma
- Molecular characterization of 7 new established cell lines from high grade serous ovarian cancer.
- Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin.
- EPO‐receptor is present in mouse C2C12 and human primary skeletal muscle cells but EPO does not influence myogenesis
- The Ovarian Cancer Chemokine Landscape is Conducive to Homing of Vaccine-primed and CD3/CD28 Costimulated T cells Prepared for Adoptive Therapy
- Hepatocellular carcinoma: Mouse models and the potential roles of proteases.
- Ovarian cancer and the immune system - The role of targeted therapies.
- CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer
- STAT1‐associated intratumoural TH1 immunity predicts chemotherapy resistance in high‐grade serous ovarian cancer
- Intratumoral interferon-gamma increases chemokine production but fails to increase T-cell infiltration of human melanoma metastases
- The pro‐fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride‐induced experimental liver injury
- A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression
- Increased STAT1 Expression in High Grade Serous Ovarian Cancer Is Associated With a Better Outcome
- Keratin-14 (KRT14) Positive Leader Cells Mediate Mesothelial Clearance and Invasion by Ovarian Cancer Cells
- Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors
- Generation of a Tumor-Specific Chemokine Gradient Using Oncolytic Vesicular Stomatitis Virus Encoding CXCL9
- Metabolism of Estrogens: Turnover Differs between Platinum-Sensitive and -Resistant High-Grade Serous Ovarian Cancer Cells
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