The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration.
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Summary
The present review analyses and discusses the evidence supporting prion-like spreading of amyloidogenic proteins, especially focusing on the cellular and molecular mechanisms and their significance.
- Type
- article
- Published
- 2013-05-15
- Cited by
- 151
- References
- 217
- OpenAlex
- https://openalex.org/W23614720
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16167276
Keywords
Humanities, Philosophy
References
- Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
- Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease*
- Can Parkinson's disease pathology be propagated from one neuron to another?
- Modulation of α7 Nicotinic Acetylcholine Receptor and Fibrillar Amyloid-β Interactions in Alzheimer's Disease Brain
- How can mammalian Rab small GTPases be comprehensively analyzed?: Development of new tools to comprehensively analyze mammalian Rabs in membrane traffic.
- α-Synuclein Oligomers: an Amyloid Pore?
- Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis
- Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats
- Retinoic acid‐ and phorbol ester‐induced neuronal differentiation down‐regulates caveolin expression in GnRH neurons
- Prions: health scare and biological challenge
- The spread of prions through the body in naturally acquired transmissible spongiform encephalopathies
- Prion-like propagation of cytosolic protein aggregates
- Intracellular amyloid-β in Alzheimer's disease
- Membrane and surface interactions of Alzheimer’s Aβ peptide – insights into the mechanism of cytotoxicity
- Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.
- Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult
- Cysteine-String Protein Increases the Calcium Sensitivity of Neurotransmitter Exocytosis in Drosophila
- Exosomes: composition, biogenesis and function
- Cysteine String Protein Is Required for Calcium Secretion Coupling of Evoked Neurotransmission in Drosophila But Not for Vesicle Recycling
- Attenuated Influx of Calcium Ions at Nerve Endings of cspand shibire Mutant Drosophila
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- SINGLE-MOLECULE ANALYSIS OF ALZHEIMER'S β-PEPTIDE OLIGOMER DISASSEMBLY AT PHYSIOLOGICAL CONCENTRATION
- Biophysical Investigations of the Aβ Aggregation Process
- Parkinsons - Just another Infectious Disease
- Cellular Prion Protein as a Therapeutic Target in Alzheimer's Disease
- Shedding light on prion disease
- Identification and Characterization of Tunneling Nanotubes for Intercellular Trafficking
- Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation
- Mediator tail subunits can form amyloid-like aggregates in vivo and affect stress response in yeast
- Prions and Prion-Like Pathogens in Neurodegenerative Disorders
- Mitochondrial dynamics in degenerative disease and disease models
- The triple power of D³: protein intrinsic disorder in degenerative diseases.
- Amyotrophic lateral sclerosis—a model of corticofugal axonal spread
- Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders
- α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
- Simulating disease propagation across white matter connectome reveals anatomical substrate for neuropathology staging in amyotrophic lateral sclerosis
- Yeast Prions and Human Prion-like Proteins: Sequence Features and Prediction Methods
- Confluence of α-synuclein, tau, and β-amyloid pathologies in dementia with Lewy bodies.
- The BiP Molecular Chaperone Plays Multiple Roles during the Biogenesis of TorsinA, an AAA+ ATPase Associated with the Neurological Disease Early-onset Torsion Dystonia*
- Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease
- Approaches for discovering anti-prion compounds: lessons learned and challenges ahead
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