Hepatitis B virus induces expression of cholesterol metabolism-related genes via TLR2 in HepG2 cells.
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Summary
Ad-HBV increases LDLR and HMGCoAr expression, resulting in exacerbated cholesterol accumulation in HepG2 cells, which was mediated via the TLR2 pathway.
- Type
- article
- Published
- 2013-04-14
- Cited by
- 43
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W23599654
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11628639
Keywords
Persona, Praxis, Sociology, Humanities, Political science
References
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- Impact of non‐alcoholic fatty liver disease on chronic hepatitis B
- Toll-like receptor signalling
- Aspirin Increases Apolipoprotein-A-I-Mediated Cholesterol Efflux via Enhancing Expression of ATP-Binding Cassette Transporter A1
- Chronic Infections and the Risk of Carotid Atherosclerosis: Prospective Results From a Large Population Study
- Hepatitis B virus replication in diverse cell types during chronic hepatitis B virus infection
- The role of the toll-like receptor TLR4 in hepatitis B virus-associated glomerulonephritis
- Regulation of the mevalonate pathway
- Correlation of Circulating TLR2/4 Expression with CD3+/4+/8+ T Cells and Treg cells in HBV-Related Liver Cirrhosis
- Overexpression of Toll-like receptor 2/4 on monocytes modulates the activities of CD4(+)CD25(+) regulatory T cells in chronic hepatitis B virus infection.
- Role of Toll-like receptors in liver health and disease.
- Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic mice.
Cited by
- Hepatitis B e antigen-positive and high levels of alanine aminotransferase are associated with prevalence of metabolic syndrome in chronic HBV patients.
- Can Toll-Like Receptor (TLR) 2 be considered as a new target for immunotherapy against hepatitis B infection?
- Clinical and laboratory characteristics associated with dyslipidemia and liver steatosis in chronic HBV carriers.
- Role of innate immunity in the development of hepatocellular carcinoma.
- Impact of hepatitis B virus infection on hepatic metabolic signaling pathway
- Plasma lipidomics identifies novel biomarkers in patients with hepatitis B virus-related acute-on-chronic liver failure
- Intracellular hepatitis B virus increases hepatic cholesterol deposition in alcoholic fatty liver via hepatitis B core protein
- Non-alcoholic hepatic steatosis attenuates hepatitis B virus replication in an HBV-immunocompetent mouse model
- Association of Serum Total Cholesterol with Pegylated Interferon-α Treatment in HBeAg-Positive Chronic Hepatitis B Patients
- The Effects of Hepatic Steatosis on the Natural History of HBV Infection.
- Anti-ApoA-1 IgGs in Familial Hypercholesterolemia Display Paradoxical Associations with Lipid Profile and Promote Foam Cell Formation
- Chronic hepatitis B and non‐alcoholic fatty liver disease: Conspirators or competitors?
- Identification of hepatitis B using Raman spectroscopy combined with gated recurrent unit and multiscale fusion convolutional neural network
- Rapid screening of hepatitis B using Raman spectroscopy and long short-term memory neural network
- Concentration of LDLR, degree of hepatic fibrosis and hepatic steatosis in patients with chronic hepatitis B infection treated with tenofovir disoproxil fumarate.
- Multifaceted Interaction Between Hepatitis B Virus Infection and Lipid Metabolism in Hepatocytes: A Potential Target of Antiviral Therapy for Chronic Hepatitis B
- Analysis and Classification of Hepatitis Infections Using Raman Spectroscopy and Multiscale Convolutional Neural Networks
- Transaminase Elevations during Treatment of Chronic Hepatitis B Infection: Safety Considerations and Role in Achieving Functional Cure
- Liver Lipids of Patients with Hepatitis B and C and Associated Hepatocellular Carcinoma
- Prevalence and Incidence of Non-alcohol Fatty Liver Disease in Chronic Hepatitis B Population in Southeast China: A Community-Based Study
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