Cancer‐associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients
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Summary
Analysis of expression of the above markers in CAF and M2 macrophages was analyzed using RT‐PCR and immunohistochemistry to demonstrate the prognostic involvement of interrelationships between DCSIGN, CD163, α‐SMA, FSP1 and FAP markers in the survival of colon cancer patients.
- Type
- article
- Published
- 2013-04-01
- Cited by
- 274
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W23298232
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14998470
Keywords
Computer science
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- Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics
- CD163+ tumor-associated macrophage is a prognostic biomarker and is associated with therapeutic effect on malignant pleural effusion of lung cancer patients
- Prognostic Significance of the Tumor-Stroma Ratio in Epithelial Ovarian Cancer
- Protumorigenic effects of Snail‐expression fibroblasts on colon cancer cells
- FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7
- Evaluation of the Radiolabeled Boronic Acid-Based FAP Inhibitor MIP-1232 for Atherosclerotic Plaque Imaging
- Fibroblast Activation Protein Overexpression and Clinical Implications in Solid Tumors: A Meta-Analysis
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- Expression, Tissue Distribution and Function of miR-21 in Esophageal Squamous Cell Carcinoma
- Pathophysiology of endotoxin tolerance: mechanisms and clinical consequences
- Prognostic significance of epithelial–mesenchymal transition-related markers in extrahepatic cholangiocarcinoma: comprehensive immunohistochemical study using a tissue microarray
- Progastrin Represses the Alternative Activation of Human Macrophages and Modulates Their Influence on Colon Cancer Epithelial Cells
- Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy.
- Tumor stroma-derived factors skew monocyte to dendritic cell differentiation toward a suppressive CD14+ PD-L1+ phenotype in prostate cancer
- IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor–stroma interaction
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