Studies of the Molecular Mechanism and Signaling Regulation of Autophagy in Saccharomyces Cerevisiae.
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Summary
Current knowledge about the machinery and molecular mechanism of autophagy, which plays a critical role during cellular development and differentiation, functions in tumor suppression, and may be linked to lifespan extension, is summarized.
- Type
- dissertation
- Published
- 2010-01-01
- Cited by
- 0
- References
- 218
- Access
- Open access
- OpenAlex
- https://openalex.org/W23241234
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:81023942
Keywords
Autophagy, Saccharomyces cerevisiae, Mechanism (biology), Cell biology, Signal transduction
References
- Amino Acids Interfere with the ERK1/2-dependent Control of Macroautophagy by Controlling the Activation of Raf-1 in Human Colon Cancer HT-29 Cells*
- Atg17 regulates the magnitude of the autophagic response.
- p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
- The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
- The Cdc28 inhibitor p40SIC1.
- Non-selective autophagy.
- An Overview of the Molecular Mechanism of Autophagy
- The Molecular Mechanism of Autophagy
- Chaperone-mediated autophagy in aging and disease.
- An arginine/histidine exchange transport system in vacuolar-membrane vesicles of Saccharomyces cerevisiae.
- The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus
- A protein conjugation system essential for autophagy
- A ubiquitin-like system mediates protein lipidation
- Yeast G1 cyclins are unstable in G1 phase
- A role for the Pcl9‐Pho85 cyclin–cdk complex at the M/G1 boundary in Saccharomyces cerevisiae
- An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells.
- A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase
- Induction of autophagy and inhibition of tumorigenesis by beclin 1
- Changes induced in the permeability barrier of the yeast plasma membrane by cupric ion
- Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy.
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