Myd88-Dependent Toll-Like Receptor 7 Signaling Mediates Protection from Severe Ross River Virus-Induced Disease in Mice
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Summary
Using a mouse model of RRV-induced myositis/arthritis, it is found that myeloid differentiation primary response gene 88 (Myd88)-dependent TLR7 signaling is involved in protection from severeRRV-associated disease.
- Type
- article
- Published
- 2012-08-01
- Cited by
- 36
- References
- 67
- OpenAlex
- https://openalex.org/W22837203
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7544817
Keywords
Geology
References
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Cited by
- Macrophage migration inhibitory factor receptor CD74 mediates alphavirus-induced arthritis and myositis in murine models of alphavirus infection.
- Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis.
- Molecular Mechanisms Involved in the Pathogenesis of Alphavirus-Induced Arthritis
- The Pathogenesis of Alphaviruses
- Ross River Virus (RRV) infection in horses and humans: a review.
- Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response
- The role of type I interferon in the immunobiology of chikungunya virus
- The protective and pathologic roles of toll-like receptors in arthritogenic alphavirus infection
- Buggy Creek Virus (Togaviridae: Alphavirus) Upregulates Expression of Pattern Recognition Receptors and Interferons in House Sparrows (Passer domesticus)
- Immune Correlates of Cross-Reactive Neutralizing Antibodies in HIV-1 Infection
- Cytokines in alphavirus induced arthritis as possible targets for novel treatments
- Ross River virus disease clinical presentation, pathogenesis and current therapeutic strategies.
- Mechanism of Alphavirus Restriction by the Interferon-Induced Exonuclease, ISG20
- INNATE IMMUNE CONTROL OF ALPHAVIRUS INFECTION
- Decreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs
- Genetic Control of Alphavirus Pathogenesis
- Sequence-Specific Extracellular MicroRNAs Activate TLR7
- Arthritogenic Alphavirus-Induced Immunopathology and Targeting Host Inflammation as A Therapeutic Strategy for Alphaviral Disease
- Arboviruses and Muscle Disorders: From Disease to Cell Biology
- Rewiring PBMC responses to prevent CHIKV infection-specific monocyte subset redistribution and cytokine responses
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